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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0043]' for entry matching: SYUA_MOUSE World-2DPAGE Repository (0043):  SYUA_MOUSE SYUA_MOUSE General information about the entry View entry in simple text format Entry name SYUA_MOUSE Primary accession number O55042 integrated into World-2DPAGE Repository (0043) on  January 4, 2012 (release 1) 2D Annotations were last modified on January 6, 2012 (version 1) General Annotations were last modified on  April 18, 2012 (version 2) Name and origin of the protein Description RecName: Full=Alpha-synuclein; AltName: Full=Non-A beta component of AD amyloid; AltName: Full=Non-A4 component of amyloid; Short=NACP;. Gene name Name=Snca Synonyms=Syn Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D GEL CHARACTERIZATION DOI=10.1016/j.jprot.2012.04.001 ; Sun Z., Biela L.M., Hamilton K.L., Reardon K.F. ''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes'' Journal of Proteomics 0(0):0-0 (2012) 2D PAGE maps for identified proteins How to interpret a protein MMUSCULUS_HL-1PHI_4-7 {mouse HL-1 cultured cardiomyocytes hydrophilic extraction} Mus musculus (Mouse) Tissue: Cardiac myocyte   map experimental info   MMUSCULUS_HL-1PHI_4-7 MAP LOCATIONS: BAND phi51: Mw=14476   [identification data] %COV: BAND phi51: 10.1 [1]. GENEID: BAND phi51: SYUA_MOUSE [1]. SCORE: BAND phi51: 437 [1]. SEARCH ENGINE: BAND phi51: Mascot [1]. MAPPING (identification): BAND phi51: Tandem mass spectrometry [1]. Copyright Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA Cross-references IPI 00115157. UniProtKB/Swiss-Prot O55042; SYUA_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2012_03 Entry name SYUA_MOUSE Primary accession number O55042 Secondary accession number(s) Q3U130 Q9CXF8 Q9EQC3 Q9QUR3 Sequence was last modified on  April 27, 2001 (version 2) Annotations were last modified on  February 22, 2012 (version 97) Name and origin of the protein Description RecName: Full=Alpha-synuclein; AltName: Full=Non-A beta component of AD amyloid; AltName: Full=Non-A4 component of amyloid precursor; Short=NACP; Gene name Name=Snca Synonyms=Syn Encoded on Name=Snca; Synonyms=Syn Keywords Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF044672; AAC00521.1; -; mRNA EMBL AF033261; AAD11254.1; -; mRNA EMBL AF179273; AAD56908.1; -; mRNA EMBL AF179272; AAD56907.1; -; Genomic_DNA EMBL AF179268; AAD56907.1; JOINED; Genomic_DNA EMBL AF179269; AAD56907.1; JOINED; Genomic_DNA EMBL AF179270; AAD56907.1; JOINED; Genomic_DNA EMBL AF179271; AAD56907.1; JOINED; Genomic_DNA EMBL AF163865; AAG30304.1; -; Genomic_DNA EMBL AK014472; BAB29375.1; -; mRNA EMBL AK156316; BAE33670.1; -; mRNA EMBL BC046764; AAH46764.1; -; mRNA EMBL AF277451; AAG44833.1; -; Genomic_DNA IPI IPI00115157; -; . IPI IPI00845803; -; . RefSeq NP_001035916.1; NM_001042451.1; . RefSeq NP_033247.1; NM_009221.2; . UniGene Mm.17484; -; . ProteinModelPortal O55042; -; . SMR O55042; 1-140; . IntAct O55042; 1; . MINT MINT-2736846; -; . STRING O55042; -; . PhosphoSite O55042; -; . PRIDE O55042; -; . Ensembl ENSMUST00000114268; ENSMUSP00000109907; ENSMUSG00000025889; . Ensembl ENSMUST00000163779; ENSMUSP00000126067; ENSMUSG00000025889; . GeneID 20617; -; . KEGG mmu:20617; -; . UCSC uc009cdn.1; mouse; . UCSC uc009cdp.1; mouse; . CTD 6622; -; . MGI MGI:1277151; Snca; . eggNOG NOG44393; -; . GeneTree ENSGT00390000016161; -; . HOGENOM HBG715579; -; . HOVERGEN HBG000481; -; . InParanoid O55042; -; . KO K04528; -; . OMA PENEAYE; -; . OrthoDB EOG4FFD3B; -; . PhylomeDB O55042; -; . NextBio 298995; -; . PMAP-CutDB O55042; -; . ArrayExpress O55042; -; . Bgee O55042; -; . CleanEx MM_SNCA; -; . Genevestigator O55042; -; . GermOnline ENSMUSG00000025889; Mus musculus; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IMP:GOC; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:MGI; . GO GO:0019717; C:synaptosome; IDA:MGI; . GO GO:0050544; F:arachidonic acid binding; IDA:MGI; . GO GO:0042393; F:histone binding; IDA:UniProtKB; . GO GO:0042802; F:identical protein binding; IDA:MGI; . GO GO:0008344; P:adult locomotory behavior; IGI:MGI; . GO GO:0034599; P:cellular response to oxidative stress; IMP:MGI; . GO GO:0042416; P:dopamine biosynthetic process; IMP:MGI; . GO GO:0006631; P:fatty acid metabolic process; IMP:MGI; . GO GO:0060291; P:long-term synaptic potentiation; IMP:MGI; . GO GO:0001774; P:microglial cell activation; IMP:MGI; . GO GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IMP:MGI; . GO GO:0007006; P:mitochondrial membrane organization; IMP:MGI; . GO GO:0043524; P:negative regulation of neuron apoptosis; IGI:MGI; . GO GO:0006638; P:neutral lipid metabolic process; IMP:MGI; . GO GO:0006644; P:phospholipid metabolic process; IMP:MGI; . GO GO:0001956; P:positive regulation of neurotransmitter secretion; IDA:MGI; . GO GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL; . GO GO:0050812; P:regulation of acyl-CoA biosynthetic process; IDA:MGI; . GO GO:0014059; P:regulation of dopamine secretion; IGI:MGI; . GO GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI; . GO GO:0014048; P:regulation of glutamate secretion; IMP:MGI; . GO GO:0040012; P:regulation of locomotion; IMP:MGI; . GO GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI; . GO GO:0043030; P:regulation of macrophage activation; IMP:MGI; . GO GO:0042493; P:response to drug; IMP:MGI; . GO GO:0001963; P:synaptic transmission; dopaminergic; IMP:MGI GO GO:0048488; P:synaptic vesicle endocytosis; IMP:UniProtKB; . InterPro IPR001058; Synuclein; . InterPro IPR002460; Synuclein_alpha; . Gene3D G3DSA:1.10.287.700; Synuclein; 1; . PANTHER PTHR13820; Synuclein; 1; . Pfam PF01387; Synuclein; 1; . PRINTS PR01212; ASYNUCLEIN; . PRINTS PR01211; SYNUCLEIN; . World-2DPAGE Repository (search AC)