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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0019]' for entry
matching:
TBA1A_MOUSE
World-2DPAGE Repository
(0019):
TBA1A_MOUSE
TBA1A_MOUSE
General information about the entry
View entry in simple text format
Entry name
TBA1A_MOUSE
Primary accession number
P68369
integrated into World-2DPAGE Repository (0019) on
December 9, 2009 (release 1)
2D Annotations were last modified on
May 30, 2011 (version 2)
General Annotations were last modified on
January 13, 2012 (version 2)
Name and origin of the protein
Description
RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain;.
Gene name
Name=Tuba1a
Synonyms=Tuba1
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1111/j.1471-4159.2010.06719.x
;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
HIPP_SYNAP
{Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
map experimental info
HIPP_SYNAP
MAP LOCATIONS:
SPOT 1167
:
pI=4.94; Mw=50787
[identification data]
IDENTIFICATION:
SPOT 1167: Peptides number=8. SeqCov=24.4%. MOWSE score=2.40E+11 [
1
].
MAPPING (identification):
SPOT
1167
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-Prot
P68369; TBA1A_MOUSE.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
TBA1A_MOUSE
Primary accession number
P68369
Secondary accession number(s)
P02551 P05210 P05212 Q3TGF0 Q3TIW2 Q3TPJ1 Q3ULN1 Q5XJF8
Sequence was last modified on
July 21, 1986 (version 1)
Annotations were last modified on
November 16, 2011 (version 83)
Name and origin of the protein
Description
RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain;
Gene name
Name=Tuba1a
Synonyms=Tuba1
Encoded on
Name=Tuba1a; Synonyms=Tuba1
Keywords
Acetylation
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Direct protein sequencing
;
GTP-binding
;
Microtubule
;
Nucleotide-binding
;
Phosphoprotein
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M13445; AAA40499.1
; -; mRNA
EMBL
AK077529; BAC36848.1
; -; mRNA
EMBL
AK145404; BAE26417.1
; -; mRNA
EMBL
AK146983; BAE27586.1
; -; mRNA
EMBL
AK164335; BAE37745.1
; -; mRNA
EMBL
AK167687; BAE39734.1
; -; mRNA
EMBL
AK168762; BAE40598.1
; -; mRNA
EMBL
AK169610; BAE41258.1
; -; mRNA
EMBL
BC056169; AAH56169.1
; -; mRNA
EMBL
BC083343; AAH83343.1
; -; mRNA
EMBL
BC083345; AAH83345.1
; -; mRNA
EMBL
BC085256; AAH85256.1
; -; mRNA
EMBL
M28729; AAA40506.1
; -; mRNA
EMBL
BC083344; AAH83344.1
; -; mRNA
IPI
IPI00110753; -
; .
PIR
I77424; I77424
; .
RefSeq
NP_035783.1; NM_011653.2
; .
UniGene
Mm.439690; -
; .
ProteinModelPortal
P68369; -
; .
SMR
P68369; 1-440
; .
IntAct
P68369; 9
; .
MINT
MINT-3288915; -
; .
STRING
P68369; -
; .
PhosphoSite
P68369; -
; .
SWISS-2DPAGE
P68369; -
; .
PRIDE
P68369; -
; .
Ensembl
ENSMUST00000097014; ENSMUSP00000094778
; ENSMUSG00000072235; .
GeneID
22142; -
; .
KEGG
mmu:22142; -
; .
CTD
7846; -
; .
MGI
MGI:98869; Tuba1a
; .
GeneTree
ENSGT00600000084100; -
; .
HOVERGEN
HBG000089; -
; .
InParanoid
P68369; -
; .
OMA
ANHEANS; -
; .
OrthoDB
EOG44J2HZ; -
; .
PhylomeDB
P68369; -
; .
NextBio
302038; -
; .
PMAP-CutDB
P68369; -
; .
ArrayExpress
P68369; -
; .
Bgee
P68369; -
; .
CleanEx
MM_TUBA1A; -
; .
Genevestigator
P68369; -
; .
GermOnline
ENSMUSG00000072235; Mus musculus
; .
GO
GO:0005881; C:cytoplasmic microtubule
; IDA:MGI; .
GO
GO:0005525; F:GTP binding
; IEA:UniProtKB-KW; .
GO
GO:0003924; F:GTPase activity
; IEA:InterPro; .
GO
GO:0005198; F:structural molecule activity
; IEA:InterPro; .
GO
GO:0007018; P:microtubule-based movement
; IEA:InterPro; .
GO
GO:0051258; P:protein polymerization
; IEA:InterPro; .
InterPro
IPR002452; Alpha_tubulin
; .
InterPro
IPR008280; Tub_FtsZ_C
; .
InterPro
IPR000217; Tubulin
; .
InterPro
IPR018316; Tubulin/FtsZ_2-layer-sand-dom
; .
InterPro
IPR023123; Tubulin_C
; .
InterPro
IPR017975; Tubulin_CS
; .
InterPro
IPR003008; Tubulin_FtsZ_GTPase
; .
Gene3D
G3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom
; 1; .
Gene3D
G3DSA:1.10.287.600; Tubulin_C
; 1; .
Gene3D
G3DSA:3.40.50.1440; Tubulin_FtsZ
; 1; .
KO
K07374; -
; .
PANTHER
PTHR11588; Tubulin
; 1; .
Pfam
PF00091; Tubulin
; 1; .
Pfam
PF03953; Tubulin_C
; 1; .
PRINTS
PR01162; ALPHATUBULIN
; .
PRINTS
PR01161; TUBULIN
; .
SMART
SM00864; Tubulin
; 1; .
SMART
SM00865; Tubulin_C
; 1; .
SUPFAM
SSF55307; Tub_FtsZ_C
; 1; .
SUPFAM
SSF52490; Tubulin_FtsZ
; 1; .
PROSITE
PS00227; TUBULIN
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server