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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: TCPA_HUMAN World-2DPAGE Repository (0054):  TCPA_HUMAN TCPA_HUMAN General information about the entry View entry in simple text format Entry name TCPA_HUMAN Primary accession number P17987 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit alpha; Short=TCP-1-alpha; AltName: Full=CCT-alpha;. Gene name Name=TCP1 Synonyms=CCT1, CCTA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 600: pI=5.80; Mw=60344   [identification data] %COV: SPOT 600: 34 [1]. SCORE: SPOT 600: 608 [1]. SEARCH ENGINE: SPOT 600: Mascot [1]. MAPPING (identification): SPOT 600: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P17987; TCPA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TCPA_HUMAN Primary accession number P17987 Secondary accession number(s) E1P5B2 Q15556 Q5TCM3 Sequence was last modified on  November 1, 1990 (version 1) Annotations were last modified on  October 1, 2014 (version 155) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit alpha; Short=TCP-1-alpha; AltName: Full=CCT-alpha; Gene name Name=TCP1 Synonyms=CCT1, CCTA Encoded on Name=TCP1; Synonyms=CCT1, CCTA Keywords Acetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X52882; CAA37064.1; -; mRNA EMBL BT006969; AAP35615.1; -; mRNA EMBL AL135914; CAI21851.1; -; Genomic_DNA EMBL CH471051; EAW47616.1; -; Genomic_DNA EMBL CH471051; EAW47618.1; -; Genomic_DNA EMBL BC000665; AAH00665.1; -; mRNA EMBL M26885; AAA61059.1; -; Genomic_DNA EMBL M27272; AAA61060.1; -; Genomic_DNA EMBL M26889; AAA61060.1; JOINED; Genomic_DNA CCDS CCDS5269.1; -; . PIR S10486; S10486; . RefSeq NP_110379.2; NM_030752.2; . UniGene Hs.363137; -; . ProteinModelPortal P17987; -; . SMR P17987; 2-534; . BioGrid 112810; 91; . DIP DIP-33676N; -; . IntAct P17987; 58; . MINT MINT-4999235; -; . STRING 9606.ENSP00000317334; -; . PhosphoSite P17987; -; . DMDM 135538; -; . OGP P17987; -; . REPRODUCTION-2DPAGE IPI00290566; -; . REPRODUCTION-2DPAGE P17987; -; . UCD-2DPAGE P17987; -; . MaxQB P17987; -; . PaxDb P17987; -; . PeptideAtlas P17987; -; . PRIDE P17987; -; . DNASU 6950; -; . Ensembl ENST00000321394; ENSP00000317334; ENSG00000120438; . GeneID 6950; -; . KEGG hsa:6950; -; . UCSC uc003qsr.3; human; . CTD 6950; -; . GeneCards GC06M160199; -; . HGNC HGNC:11655; TCP1; . HPA CAB017460; -; . HPA HPA027337; -; . HPA HPA031082; -; . MIM 186980; gene; . neXtProt NX_P17987; -; . PharmGKB PA36406; -; . eggNOG COG0459; -; . HOGENOM HOG000226729; -; . HOVERGEN HBG001052; -; . InParanoid P17987; -; . KO K09493; -; . OMA IMRIDTL; -; . OrthoDB EOG7K3TKJ; -; . PhylomeDB P17987; -; . TreeFam TF106331; -; . Reactome REACT_16907; Association of TriC/CCT with target proteins during biosynthesis; . Reactome REACT_16936; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome REACT_16956; Formation of tubulin folding intermediates by CCT/TriC; . Reactome REACT_17050; Folding of actin by CCT/TriC; . ChiTaRS TCP1; human; . GeneWiki T-complex_1; -; . GenomeRNAi 6950; -; . NextBio 27215; -; . PRO PR:P17987; -; . ArrayExpress P17987; -; . Bgee P17987; -; . CleanEx HS_TCP1; -; . Genevestigator P17987; -; . GO GO:0001669; C:acrosomal vesicle; IEA:Ensembl; . GO GO:0044297; C:cell body; IEA:Ensembl; . GO GO:0005813; C:centrosome; IDA:MGI; . GO GO:0005832; C:chaperonin-containing T-complex; IEA:Ensembl; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0005794; C:Golgi apparatus; IEA:Ensembl; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0005720; C:nuclear heterochromatin; IEA:Ensembl; . GO GO:0000242; C:pericentriolar material; IEA:Ensembl; . GO GO:0002199; C:zona pellucida receptor complex; IEA:Ensembl; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0051082; F:unfolded protein binding; TAS:ProtInc; . GO GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome; . GO GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl; . GO GO:0044267; P:cellular protein metabolic process; TAS:Reactome; . GO GO:0006457; P:protein folding; TAS:Reactome; . GO GO:0007021; P:tubulin complex assembly; NAS:UniProtKB; . Gene3D 1.10.560.10; -; 2; . Gene3D 3.30.260.10; -; 2; . Gene3D 3.50.7.10; -; 1; . InterPro IPR017998; Chaperone_TCP-1; . InterPro IPR002194; Chaperonin_TCP-1_CS; . InterPro IPR002423; Cpn60/TCP-1; . InterPro IPR027409; GroEL-like_apical_dom; . InterPro IPR027413; GROEL-like_equatorial; . InterPro IPR027410; TCP-1-like_intermed; . PANTHER PTHR11353; PTHR11353; 1; . Pfam PF00118; Cpn60_TCP1; 1; . PRINTS PR00304; TCOMPLEXTCP1; . SUPFAM SSF48592; SSF48592; 2; . SUPFAM SSF52029; SSF52029; 1; . PROSITE PS00750; TCP1_1; 1; . PROSITE PS00751; TCP1_2; 1; . PROSITE PS00995; TCP1_3; 1; . World-2DPAGE Repository (search AC)