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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: TEBP_HUMAN World-2DPAGE Repository (0054):  TEBP_HUMAN TEBP_HUMAN General information about the entry View entry in simple text format Entry name TEBP_HUMAN Primary accession number Q15185 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Prostaglandin E synthase 3; EC=5.3.99.3; AltName: Full=Cytosolic prostaglandin E2 synthase; Short=cPGES; AltName: Full=Hsp90 co-chaperone; AltName: Full=Progesterone receptor complex p23; AltName: Full=Telomerase-binding protein p23;. Gene name Name=PTGES3 Synonyms=P23, TEBP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 1176: pI=4.32; Mw=18697   [identification data] %COV: SPOT 1176: 27 [1]. SCORE: SPOT 1176: 139 [1]. SEARCH ENGINE: SPOT 1176: Mascot [1]. MAPPING (identification): SPOT 1176: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q15185; TEBP_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TEBP_HUMAN Primary accession number Q15185 Secondary accession number(s) A8K7D0 B4DHP2 B4DP11 B4DP21 Q8WU70 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  October 1, 2014 (version 143) Name and origin of the protein Description RecName: Full=Prostaglandin E synthase 3; EC=5.3.99.3; AltName: Full=Cytosolic prostaglandin E2 synthase; Short=cPGES; AltName: Full=Hsp90 co-chaperone; AltName: Full=Progesterone receptor complex p23; AltName: Full=Telomerase-binding protein p23; Gene name Name=PTGES3 Synonyms=P23, TEBP Encoded on Name=PTGES3; Synonyms=P23, TEBP Keywords 3D-structure; Acetylation; Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Fatty acid biosynthesis; Fatty acid metabolism; Isomerase; Lipid biosynthesis; Lipid metabolism; Phosphoprotein; Prostaglandin biosynthesis; Prostaglandin metabolism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L24804; AAA18537.1; -; mRNA EMBL AK291945; BAF84634.1; -; mRNA EMBL AK295208; BAG58204.1; -; mRNA EMBL AK298147; BAG60423.1; -; mRNA EMBL AK298160; BAG60433.1; -; mRNA EMBL AC117378; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471054; EAW96953.1; -; Genomic_DNA EMBL CH471054; EAW96958.1; -; Genomic_DNA EMBL BC003005; AAH03005.1; -; mRNA EMBL BC021167; AAH21167.1; -; mRNA CCDS CCDS31836.1; -. [Q15185-1]; . CCDS CCDS61158.1; -. [Q15185-2]; . CCDS CCDS61159.1; -. [Q15185-3]; . CCDS CCDS61160.1; -. [Q15185-4]; . PIR A56211; A56211; . RefSeq NP_001269530.1; NM_001282601.1; . RefSeq NP_001269531.1; NM_001282602.1; . RefSeq NP_001269532.1; NM_001282603.1; . RefSeq NP_001269533.1; NM_001282604.1; . RefSeq NP_001269534.1; NM_001282605.1; . RefSeq NP_006592.3; NM_006601.6; . UniGene Hs.50425; -; . PDB 1EJF; X-ray; 2.49 A; A/B=1-125 PDB 1LG0; Model; -; A=1-110 PDBsum 1EJF; -; . PDBsum 1LG0; -; . DisProt DP00358; -; . ProteinModelPortal Q15185; -; . SMR Q15185; 1-110; . BioGrid 115952; 61; . DIP DIP-279N; -; . IntAct Q15185; 37; . MINT MINT-5000397; -; . STRING 9606.ENSP00000262033; -; . PhosphoSite Q15185; -; . MaxQB Q15185; -; . PaxDb Q15185; -; . PRIDE Q15185; -; . DNASU 10728; -; . Ensembl ENST00000262033; ENSP00000262033; ENSG00000110958. [Q15185-1]; . Ensembl ENST00000414274; ENSP00000405299; ENSG00000110958. [Q15185-3]; . Ensembl ENST00000436399; ENSP00000402385; ENSG00000110958. [Q15185-2]; . Ensembl ENST00000448157; ENSP00000414892; ENSG00000110958. [Q15185-4]; . GeneID 10728; -; . KEGG hsa:10728; -; . UCSC uc001slu.4; human. [Q15185-1]; . CTD 10728; -; . GeneCards GC12M057057; -; . HGNC HGNC:16049; PTGES3; . HPA CAB034319; -; . HPA HPA038672; -; . HPA HPA038673; -; . MIM 607061; gene; . neXtProt NX_Q15185; -; . PharmGKB PA142671118; -; . eggNOG NOG283591; -; . HOVERGEN HBG002143; -; . InParanoid Q15185; -; . KO K15730; -; . OMA VNIKTPD; -; . OrthoDB EOG77HDGK; -; . PhylomeDB Q15185; -; . TreeFam TF315077; -; . BioCyc MetaCyc:HS03359-MONOMER; -; . Reactome REACT_150149; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); . Reactome REACT_200624; Attenuation phase; . Reactome REACT_200744; HSF1 activation; . UniPathway UPA00662; -; . ChiTaRS PTGES3; human; . EvolutionaryTrace Q15185; -; . GeneWiki PTGES3; -; . GenomeRNAi 10728; -; . NextBio 35472063; -; . PRO PR:Q15185; -; . ArrayExpress Q15185; -; . Bgee Q15185; -; . CleanEx HS_PTGES3; -; . Genevestigator Q15185; -; . GO GO:0000781; C:chromosome; telomeric region; IC:UniProtKB GO GO:0005737; C:cytoplasm; IDA:HPA; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0005634; C:nucleus; IDA:UniProt; . GO GO:0005697; C:telomerase holoenzyme complex; IDA:UniProtKB; . GO GO:0050220; F:prostaglandin-E synthase activity; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0003720; F:telomerase activity; IDA:UniProtKB; . GO GO:0051082; F:unfolded protein binding; IDA:UniProtKB; . GO GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome; . GO GO:0070389; P:chaperone cofactor-dependent protein refolding; IDA:UniProtKB; . GO GO:0019371; P:cyclooxygenase pathway; TAS:Reactome; . GO GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB; . GO GO:0006278; P:RNA-dependent DNA replication; IDA:GOC; . GO GO:0007165; P:signal transduction; TAS:ProtInc; . GO GO:0044281; P:small molecule metabolic process; TAS:Reactome; . GO GO:0000723; P:telomere maintenance; TAS:UniProtKB; . Gene3D 2.60.40.790; -; 1; . InterPro IPR007052; CS_dom; . InterPro IPR008978; HSP20-like_chaperone; . Pfam PF04969; CS; 1; . SUPFAM SSF49764; SSF49764; 1; . PROSITE PS51203; CS; 1; . World-2DPAGE Repository (search AC)