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Searching in 'World-2DPAGE Repository [0043]' for entry matching: TPM1_MOUSE

World-2DPAGE Repository (0043):  TPM1_MOUSE


General information about the entry
View entry in simple text format
Entry nameTPM1_MOUSE
Primary accession numberP58771
integrated into World-2DPAGE Repository (0043) on January 4, 2012 (release 1)
2D Annotations were last modified onJanuary 6, 2012 (version 1)
General Annotations were last modified on April 18, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Tropomyosin alpha-1 chain; AltName: Full=Alpha-tropomyosin; AltName: Full=Tropomyosin-1;.
Gene nameName=Tpm1
Synonyms=Tpm-1, Tpma
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
DOI=10.1016/j.jprot.2012.04.001 ;
Sun Z., Biela L.M., Hamilton K.L., Reardon K.F.
''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes''
Journal of Proteomics 0(0):0-0 (2012)
2D PAGE maps for identified proteins
How to interpret a protein

MMUSCULUS_HL-1PHO_4-7 {mouse HL-1 cultured cardiomyocytes hydrophobic extraction}
Mus musculus (Mouse)
Tissue: Cardiac myocyte
  map experimental info

Mw=32718  [identification data]
Mw=32718  [identification data]

%COV: BAND pho14: 15.6 [1]
BAND pho16: 20 [1].
BAND pho16: TPM1_MOUSE [1].
SCORE: BAND pho14: 578 [1]
BAND pho16: 345 [1].
SEARCH ENGINE: BAND pho14: Mascot [1]
BAND pho16: Mascot [1].
MAPPING (identification):
BAND pho14: Tandem mass spectrometry [1];
BAND pho16: Tandem mass spectrometry [1].

Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA
UniProtKB/Swiss-ProtP58771; TPM1_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2012_03
Entry nameTPM1_MOUSE
Primary accession numberP58771
Secondary accession number(s) P02558 P19354 P46902 P99034
Sequence was last modified on July 21, 1986 (version 1)
Annotations were last modified on February 22, 2012 (version 83)
Name and origin of the protein
DescriptionRecName: Full=Tropomyosin alpha-1 chain; AltName: Full=Alpha-tropomyosin; AltName: Full=Tropomyosin-1;
Gene nameName=Tpm1
Synonyms=Tpm-1, Tpma
Encoded onName=Tpm1; Synonyms=Tpm-1, Tpma
KeywordsAcetylation; Actin-binding; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Isopeptide bond; Muscle protein; Phosphoprotein; Reference proteome; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX64831; CAA46043.1; -; mRNA
EMBLM22479; AAA40483.1; -; mRNA
IPIIPI00123316; -; .
IPIIPI00227835; -; .
PIRA31380; A60597; .
RefSeqNP_001157720.1; NM_001164248.1; .
RefSeqNP_077745.2; NM_024427.4; .
UniGeneMm.121878; -; .
ProteinModelPortalP58771; -; .
SMRP58771; 8-284; .
DIPDIP-300N; -; .
IntActP58771; 6; .
STRINGP58771; -; .
PhosphoSiteP58771; -; .
SWISS-2DPAGEP58771; -; .
PRIDEP58771; -; .
EnsemblENSMUST00000113685; ENSMUSP00000109315; ENSMUSG00000032366; .
EnsemblENSMUST00000113707; ENSMUSP00000109337; ENSMUSG00000032366; .
GeneID22003; -; .
KEGGmmu:22003; -; .
CTD7168; -; .
MGIMGI:98809; Tpm1; .
eggNOGNOG304012; -; .
GeneTreeENSGT00550000074494; -; .
HOVERGENHBG107404; -; .
KOK10373; -; .
OrthoDBEOG4TXBSM; -; .
ArrayExpressP58771; -; .
BgeeP58771; -; .
CleanExMM_TPM1; -; .
GenevestigatorP58771; -; .
GermOnlineENSMUSG00000032366; Mus musculus; .
GOGO:0005862; C:muscle thin filament tropomyosin; TAS:MGI; .
GOGO:0003779; F:actin binding; IEA:UniProtKB-KW; .
GOGO:0005200; F:structural constituent of cytoskeleton; TAS:MGI; .
GOGO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL; .
GOGO:0001701; P:in utero embryonic development; IMP:MGI; .
GOGO:0003065; P:positive regulation of heart rate by epinephrine; IMP:BHF-UCL; .
GOGO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL; .
InterProIPR000533; Tropomyosin; .
PfamPF00261; Tropomyosin; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server