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Searching in 'World-2DPAGE Repository [0022]' for entry matching: TRFE_RAT




World-2DPAGE Repository (0022):  TRFE_RAT


TRFE_RAT


General information about the entry
View entry in simple text format
Entry nameTRFE_RAT
Primary accession numberP12346
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serotransferrin; Short=Transferrin; AltName: Full=Beta-1 metal-binding globulin; AltName: Full=Liver regeneration-related protein LRRG03; AltName: Full=Siderophilin; Flags: Precursor;.
Gene nameName=Tf
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=7.14; Mw=78512  [identification data]
pI=7.14; Mw=78512  [identification data]
pI=7.14; Mw=78512  [identification data]

IDENTIFICATION: SPOT 833: SeqCov=26.9%. Peptides MS=7/20. Mascot PMF Score=132 [1]
SPOT 861: SeqCov=26.9%. Peptides MS=13/20. Mascot PMF Score=132 [1]; SPOT 867: SeqCov=18.6%. Peptides MS=7/20. Mascot PMF Score=74 [1].
PEPTIDE EVIDENCE: SPOT 867: 144-SAGWIIPIGLLFCNLPEPR-162 (33) / 660-LPEGTTYEEYLGAEYLQAVGNIR-682 (64) [1].
MAPPING (identification):
SPOT 833: Peptide mass fingerprinting [1];
SPOT 861: Peptide mass fingerprinting [1];
SPOT 867: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP12346; TRFE_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameTRFE_RAT
Primary accession numberP12346
Secondary accession number(s) Q63602 Q64628 Q64630 Q7TNX0
Sequence was last modified on January 9, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 108)
Name and origin of the protein
DescriptionRecName: Full=Serotransferrin; Short=Transferrin; AltName: Full=Beta-1 metal-binding globulin; AltName: Full=Liver regeneration-related protein LRRG03; AltName: Full=Siderophilin; Flags: Precursor;
Gene nameName=Tf
Encoded onName=Tf
KeywordsAlternative splicing; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Ion transport; Iron; Iron transport; Metal-binding; Methylation; Phosphoprotein; Reference proteome; Repeat; Secreted; Signal; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX77158; CAA54403.1; -; mRNA
EMBLD38380; BAA07458.1; -; mRNA
EMBLAY327504; AAP97736.1; -; mRNA
EMBLBC087021; AAH87021.1; -; mRNA
EMBLM26113; AAA42266.1; -; mRNA
EMBLM27966; AAA42267.1; -; mRNA
IPIIPI00475946; -; .
IPIIPI00679202; -; .
PIRS49163; S49163; .
RefSeqNP_001013128.1; NM_001013110.1; .
UniGeneRn.91296; -; .
ProteinModelPortalP12346; -; .
SMRP12346; 22-697; .
STRINGP12346; -; .
Allergome1417; Rat n Transferrin; .
MEROPSS60.972; -; .
GlycoSuiteDBP12346; -; .
PhosphoSiteP12346; -; .
World-2DPAGE0004:P12346; -; .
PRIDEP12346; -; .
EnsemblENSRNOT00000012946; ENSRNOP00000012946; ENSRNOG00000030625; .
EnsemblENSRNOT00000045628; ENSRNOP00000045637; ENSRNOG00000030625; .
GeneID24825; -; .
KEGGrno:24825; -; .
UCSCNM_001013110; rat; .
CTD7018; -; .
RGD3845; Tf; .
eggNOGroNOG10662; -; .
GeneTreeENSGT00390000001619; -; .
HOVERGENHBG000055; -; .
NextBio604536; -; .
ArrayExpressP12346; -; .
GenevestigatorP12346; -; .
GermOnlineENSRNOG00000030625; Rattus norvegicus; .
GOGO:0005604; C:basement membrane; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0008199; F:ferric iron binding; IDA:RGD; .
GOGO:0015091; F:ferric iron transmembrane transporter activity; IDA:RGD; .
GOGO:0006953; P:acute-phase response; IEP:RGD; .
GOGO:0006879; P:cellular iron ion homeostasis; TAS:RGD; .
GOGO:0071320; P:cellular response to cAMP; IEP:UniProtKB; .
GOGO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:UniProtKB; .
GOGO:0031643; P:positive regulation of myelination; IDA:RGD; .
GOGO:0001666; P:response to hypoxia; IEP:RGD; .
GOGO:0014070; P:response to organic cyclic compound; IEP:RGD; .
InterProIPR001156; Peptidase_S60; .
InterProIPR016357; Transferrin; .
InterProIPR018195; Transferrin_Fe_BS; .
KOK14736; -; .
PANTHERPTHR11485; Peptidase_S60; 1; .
PfamPF00405; Transferrin; 2; .
PIRSFPIRSF002549; Transferrin; 1; .
PRINTSPR00422; TRANSFERRIN; .
SMARTSM00094; TR_FER; 2; .
PROSITEPS00205; TRANSFERRIN_LIKE_1; 1; .
PROSITEPS00206; TRANSFERRIN_LIKE_2; 2; .
PROSITEPS00207; TRANSFERRIN_LIKE_3; 2; .
PROSITEPS51408; TRANSFERRIN_LIKE_4; 2; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server