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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: TYY1_HUMAN World-2DPAGE Repository (0054):  TYY1_HUMAN TYY1_HUMAN General information about the entry View entry in simple text format Entry name TYY1_HUMAN Primary accession number P25490 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Transcriptional repressor protein YY1; AltName: Full=Delta transcription factor; AltName: Full=INO80 complex subunit S; AltName: Full=NF-E1; AltName: Full=Yin and yang 1; Short=YY-1;. Gene name Name=YY1 Synonyms=INO80S Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 613: pI=5.80; Mw=44713   [identification data] %COV: SPOT 613: 30 [1]. SCORE: SPOT 613: 574 [1]. SEARCH ENGINE: SPOT 613: Mascot [1]. MAPPING (identification): SPOT 613: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P25490; TYY1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TYY1_HUMAN Primary accession number P25490 Secondary accession number(s) Q14935 Sequence was last modified on  December 15, 1998 (version 2) Annotations were last modified on  October 1, 2014 (version 169) Name and origin of the protein Description RecName: Full=Transcriptional repressor protein YY1; AltName: Full=Delta transcription factor; AltName: Full=INO80 complex subunit S; AltName: Full=NF-E1; AltName: Full=Yin and yang 1; Short=YY-1; Gene name Name=YY1 Synonyms=INO80S Encoded on Name=YY1; Synonyms=INO80S Keywords 3D-structure; Activator; ADP-ribosylation; Complete proteome; Differentiation; Direct protein sequencing; DNA damage; DNA recombination; DNA repair; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Spermatogenesis; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M77698; AAA59467.1; -; mRNA EMBL M76541; AAA59926.1; -; mRNA EMBL Z14077; CAA78455.1; -; mRNA EMBL BC037308; AAH37308.1; -; mRNA EMBL BC065366; AAH65366.1; -; mRNA CCDS CCDS9957.1; -; . PIR A40350; A40350; . RefSeq NP_003394.1; NM_003403.4; . UniGene Hs.388927; -; . UniGene Hs.603118; -; . PDB 1UBD; X-ray; 2.50 A; C=291-414 PDB 1ZNM; NMR; -; A=352-379 PDB 4C5I; X-ray; 2.59 A; C=199-228 PDBsum 1UBD; -; . PDBsum 1ZNM; -; . PDBsum 4C5I; -; . ProteinModelPortal P25490; -; . SMR P25490; 295-408; . BioGrid 113360; 119; . DIP DIP-150N; -; . IntAct P25490; 41; . MINT MINT-157439; -; . STRING 9606.ENSP00000262238; -; . PhosphoSite P25490; -; . DMDM 3915889; -; . MaxQB P25490; -; . PaxDb P25490; -; . PeptideAtlas P25490; -; . PRIDE P25490; -; . DNASU 7528; -; . Ensembl ENST00000262238; ENSP00000262238; ENSG00000100811; . GeneID 7528; -; . KEGG hsa:7528; -; . UCSC uc001ygy.2; human; . CTD 7528; -; . GeneCards GC14P101161; -; . HGNC HGNC:12856; YY1; . HPA CAB009392; -; . HPA HPA001119; -; . MIM 600013; gene; . neXtProt NX_P25490; -; . PharmGKB PA37445; -; . eggNOG COG5048; -; . HOGENOM HOG000008232; -; . HOVERGEN HBG006823; -; . InParanoid P25490; -; . KO K09201; -; . OMA DIDHESV; -; . PhylomeDB P25490; -; . TreeFam TF106493; -; . SignaLink P25490; -; . ChiTaRS YY1; human; . EvolutionaryTrace P25490; -; . GeneWiki YY1; -; . GenomeRNAi 7528; -; . NextBio 29449; -; . PMAP-CutDB P25490; -; . PRO PR:P25490; -; . ArrayExpress P25490; -; . Bgee P25490; -; . CleanEx HS_YY1; -; . Genevestigator P25490; -; . GO GO:0031011; C:Ino80 complex; IDA:UniProtKB; . GO GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0031519; C:PcG protein complex; IEA:Ensembl; . GO GO:0005667; C:transcription factor complex; IEA:Ensembl; . GO GO:0003677; F:DNA binding; IDA:MGI; . GO GO:0000400; F:four-way junction DNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:MGI; . GO GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL; . GO GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc; . GO GO:0003713; F:transcription coactivator activity; TAS:ProtInc; . GO GO:0003714; F:transcription corepressor activity; TAS:ProtInc; . GO GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI; . GO GO:0008270; F:zinc ion binding; TAS:ProtInc; . GO GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl; . GO GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl; . GO GO:0030154; P:cell differentiation; IEA:UniProtKB-KW; . GO GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB; . GO GO:0034644; P:cellular response to UV; IMP:UniProtKB; . GO GO:0051276; P:chromosome organization; IEA:Ensembl; . GO GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB; . GO GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI; . GO GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc; . GO GO:0034696; P:response to prostaglandin F; IEA:Ensembl; . GO GO:0010225; P:response to UV-C; IMP:UniProtKB; . GO GO:0006403; P:RNA localization; IEA:Ensembl; . GO GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW; . Gene3D 3.30.160.60; -; 4; . InterPro IPR017114; TF_Yin_yang; . InterPro IPR007087; Znf_C2H2; . InterPro IPR015880; Znf_C2H2-like; . InterPro IPR013087; Znf_C2H2/integrase_DNA-bd; . Pfam PF00096; zf-C2H2; 1; . PIRSF PIRSF037113; TF_Yin_yang; 1; . SMART SM00355; ZnF_C2H2; 4; . PROSITE PS00028; ZINC_FINGER_C2H2_1; 4; . PROSITE PS50157; ZINC_FINGER_C2H2_2; 4; . World-2DPAGE Repository (search AC)