Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: U2AF2_HUMAN World-2DPAGE Repository (0054):  U2AF2_HUMAN U2AF2_HUMAN General information about the entry View entry in simple text format Entry name U2AF2_HUMAN Primary accession number P26368 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Splicing factor U2AF 65 kDa subunit; AltName: Full=U2 auxiliary factor 65 kDa subunit; Short=hU2AF(65); Short=hU2AF65; AltName: Full=U2 snRNP auxiliary factor large subunit;. Gene name Name=U2AF2 Synonyms=U2AF65 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 633: pI=9.19; Mw=53370   [identification data] %COV: SPOT 633: 40 [1]. SCORE: SPOT 633: 473 [1]. SEARCH ENGINE: SPOT 633: Mascot [1]. MAPPING (identification): SPOT 633: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P26368; U2AF2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name U2AF2_HUMAN Primary accession number P26368 Secondary accession number(s) Q96HC5 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  October 1, 2014 (version 168) Name and origin of the protein Description RecName: Full=Splicing factor U2AF 65 kDa subunit; AltName: Full=U2 auxiliary factor 65 kDa subunit; Short=hU2AF(65); Short=hU2AF65; AltName: Full=U2 snRNP auxiliary factor large subunit; Gene name Name=U2AF2 Synonyms=U2AF65 Encoded on Name=U2AF2; Synonyms=U2AF65 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Hydroxylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding; Spliceosome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X64044; CAA45409.1; -; mRNA EMBL CH471135; EAW72404.1; -; Genomic_DNA EMBL BC008740; AAH08740.1; -; mRNA EMBL BC030574; AAH30574.1; -; mRNA CCDS CCDS12933.1; -. [P26368-1]; . CCDS CCDS46197.1; -. [P26368-2]; . PIR S20250; S20250; . RefSeq NP_001012496.1; NM_001012478.1. [P26368-2]; . RefSeq NP_009210.1; NM_007279.2. [P26368-1]; . UniGene Hs.528007; -; . PDB 1JMT; X-ray; 2.20 A; B=85-112 PDB 1O0P; NMR; -; A=372-475 PDB 1OPI; NMR; -; A=372-475 PDB 1U2F; NMR; -; A=148-237 PDB 2G4B; X-ray; 2.50 A; A=148-336 PDB 2HZC; X-ray; 1.47 A; A=148-229 PDB 2M0G; NMR; -; B=372-475 PDB 2U2F; NMR; -; A=258-342 PDB 2YH0; NMR; -; A=148-342 PDB 2YH1; NMR; -; A=148-342 PDB 3VAF; X-ray; 2.49 A; A/B=148-336 PDB 3VAG; X-ray; 2.19 A; A/B=148-336 PDB 3VAH; X-ray; 2.50 A; A/B=148-336 PDB 3VAI; X-ray; 2.20 A; A/B=148-336 PDB 3VAJ; X-ray; 1.90 A; A/B=148-336 PDB 3VAK; X-ray; 2.17 A; A/B=148-336 PDB 3VAL; X-ray; 2.50 A; A/B/D/I=148-336 PDB 3VAM; X-ray; 2.40 A; A/B=148-336 PDB 4FXW; X-ray; 2.29 A; A/C=375-475 PDBsum 1JMT; -; . PDBsum 1O0P; -; . PDBsum 1OPI; -; . PDBsum 1U2F; -; . PDBsum 2G4B; -; . PDBsum 2HZC; -; . PDBsum 2M0G; -; . PDBsum 2U2F; -; . PDBsum 2YH0; -; . PDBsum 2YH1; -; . PDBsum 3VAF; -; . PDBsum 3VAG; -; . PDBsum 3VAH; -; . PDBsum 3VAI; -; . PDBsum 3VAJ; -; . PDBsum 3VAK; -; . PDBsum 3VAL; -; . PDBsum 3VAM; -; . PDBsum 4FXW; -; . ProteinModelPortal P26368; -; . SMR P26368; 148-475; . BioGrid 116466; 129; . DIP DIP-2154N; -; . IntAct P26368; 49; . MINT MINT-1192370; -; . STRING 9606.ENSP00000307863; -; . PhosphoSite P26368; -; . DMDM 267188; -; . MaxQB P26368; -; . PaxDb P26368; -; . PRIDE P26368; -; . DNASU 11338; -; . Ensembl ENST00000308924; ENSP00000307863; ENSG00000063244. [P26368-1]; . Ensembl ENST00000450554; ENSP00000388475; ENSG00000063244. [P26368-2]; . GeneID 11338; -; . KEGG hsa:11338; -; . UCSC uc002qlt.3; human. [P26368-2]; . UCSC uc002qlu.3; human. [P26368-1]; . CTD 11338; -; . GeneCards GC19P056165; -; . HGNC HGNC:23156; U2AF2; . HPA CAB010910; -; . HPA HPA041943; -; . HPA HPA043562; -; . MIM 191318; gene; . neXtProt NX_P26368; -; . PharmGKB PA134908683; -; . eggNOG NOG298004; -; . HOGENOM HOG000180745; -; . HOVERGEN HBG062169; -; . InParanoid P26368; -; . KO K12837; -; . OMA YARRETR; -; . OrthoDB EOG7CNZFZ; -; . PhylomeDB P26368; -; . TreeFam TF314111; -; . Reactome REACT_1597; Transport of Mature mRNA derived from an Intron-Containing Transcript; . Reactome REACT_1849; mRNA 3'-end processing; . Reactome REACT_467; mRNA Splicing - Major Pathway; . ChiTaRS U2AF2; human; . EvolutionaryTrace P26368; -; . GeneWiki U2AF2; -; . GenomeRNAi 11338; -; . NextBio 43079; -; . PMAP-CutDB P26368; -; . PRO PR:P26368; -; . ArrayExpress P26368; -; . Bgee P26368; -; . CleanEx HS_U2AF2; -; . Genevestigator P26368; -; . GO GO:0016607; C:nuclear speck; IDA:MGI; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:HPA; . GO GO:0005681; C:spliceosomal complex; IDA:HGNC; . GO GO:0019899; F:enzyme binding; IPI:UniProtKB; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0031124; P:mRNA 3'-end processing; TAS:Reactome; . GO GO:0006406; P:mRNA export from nucleus; TAS:Reactome; . GO GO:0006397; P:mRNA processing; TAS:ProtInc; . GO GO:0000398; P:mRNA splicing; via spliceosome; IC:HGNC GO GO:0048025; P:negative regulation of mRNA splicing; via spliceosome; IDA:UniProtKB GO GO:0008380; P:RNA splicing; TAS:Reactome; . GO GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome; . GO GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome; . Gene3D 3.30.70.330; -; 3; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . InterPro IPR006529; U2AF_lg; . Pfam PF00076; RRM_1; 2; . SMART SM00360; RRM; 3; . TIGRFAMs TIGR01642; U2AF_lg; 1; . PROSITE PS50102; RRM; 3; . World-2DPAGE Repository (search AC)