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Sample Preparation and Post-separation Analysis
| Searching in 'SWISS-2DPAGE' for entry matching: A2MG_HUMAN |
SWISS-2DPAGE: A2MG_HUMAN
A2MG_HUMAN:
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ID A2MG_HUMAN; STANDARD; 2DG.
AC P01023;
DT 01-AUG-1993, integrated into SWISS-2DPAGE (release 0).
DT 01-DEC-2000, 2D annotation version 1.
DT 19-MAY-2011, general annotation version 10.
DE RecName: Full=Alpha-2-macroglobulin; Short=Alpha-2-M; AltName: Full=C3
DE and PZP-like alpha-2-macroglobulin domain-containing protein 5; Flags: Precursor;.
GN Name=A2M; Synonyms=CPAMD5; ORFNames=FWP007;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Hominidae; Homo.
OX NCBI_TaxID=9606;
MT HEPG2SP_HUMAN, PLASMA_HUMAN.
IM HEPG2SP_HUMAN, PLASMA_HUMAN.
RN [1]
RP MAPPING ON GEL.
RX MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan]
RA Anderson N.L., Anderson N.G.;
RT ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'';
RL Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977).
RN [2]
RP MAPPING ON GEL.
RX MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
RA Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch
RA A., Hochstrasser D.F.;
RT ''''''Inside SWISS-2DPAGE database'';'';'';
RL Electrophoresis 16(1):1131-1151(1995).
CC -!- SUBUNIT: HOMOTETRAMER
2D -!- MASTER: HEPG2SP_HUMAN;
2D -!- PI/MW: SPOT 2D-0008HD=5.48/184836;
2D -!- PI/MW: SPOT 2D-0008HE=5.45/183797;
2D -!- PI/MW: SPOT 2D-0008HF=5.51/183797;
2D -!- PI/MW: SPOT 2D-0008HG=5.98/183797;
2D -!- PI/MW: SPOT 2D-0008HK=5.41/182764;
2D -!- PI/MW: SPOT 2D-0008HL=5.53/182764;
2D -!- PI/MW: SPOT 2D-0008HM=5.57/183797;
2D -!- PI/MW: SPOT 2D-0008HN=5.63/182764;
2D -!- PI/MW: SPOT 2D-0008HO=5.66/182764;
2D -!- PI/MW: SPOT 2D-0008HP=5.70/182764;
2D -!- PI/MW: SPOT 2D-0008HQ=5.73/182764;
2D -!- PI/MW: SPOT 2D-0008HR=5.77/182764;
2D -!- PI/MW: SPOT 2D-0008HS=5.80/182764;
2D -!- PI/MW: SPOT 2D-0008HT=5.85/182764;
2D -!- PI/MW: SPOT 2D-0008HU=5.88/182764;
2D -!- PI/MW: SPOT 2D-0008HV=5.91/182764;
2D -!- PI/MW: SPOT 2D-0008HW=5.94/183797;
2D -!- PI/MW: SPOT 2D-0008HZ=5.39/181737;
2D -!- PI/MW: SPOT 2D-0008I0=5.60/181737;
2D -!- PI/MW: SPOT 2D-0008I1=5.33/181737;
2D -!- PI/MW: SPOT 2D-0008I2=5.35/181737;
2D -!- PI/MW: SPOT 2D-0008I3=5.37/181737;
2D -!- MAPPING: MATCHING WITH THE PLASMA MASTER GEL [2].
2D -!- MASTER: PLASMA_HUMAN;
2D -!- PI/MW: SPOT 2D-000457=5.33/190595;
2D -!- PI/MW: SPOT 2D-000458=5.36/190595;
2D -!- PI/MW: SPOT 2D-00045C=5.40/189274;
2D -!- PI/MW: SPOT 2D-00045D=5.43/187962;
2D -!- PI/MW: SPOT 2D-00045E=5.47/186659;
2D -!- PI/MW: SPOT 2D-00045F=5.52/186659;
2D -!- PI/MW: SPOT 2D-00045G=5.55/186659;
2D -!- PI/MW: SPOT 2D-00045H=5.57/186659;
2D -!- PI/MW: SPOT 2D-00045I=5.59/186659;
2D -!- PI/MW: SPOT 2D-00045J=5.61/186659;
2D -!- PI/MW: SPOT 2D-00045K=5.62/186659;
2D -!- NORMAL LEVEL: 1500-4000 MG/L.
2D -!- PATHOLOGICAL LEVEL: DECREASED DURING FIBRINOLYSIS AND ACUTE
2D PANCREATITIS; INCREASED DURING NEPHROTIC SYNDROME, LIVER DISEASE,
2D DIABETES MELLITUS AND INFLAMMATORY DISEASE.
2D -!- POSITIONAL VARIANTS: CLASSIFIED IN THE XM SYSTEM.
2D -!- MAPPING: IMMUNOBLOTTING [1].
CC ---------------------------------------------------------------------------
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CC its content is in no way modified and this statement is not removed.
CC Usage by and for commercial entities requires a license agreement (See
CC http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
CC ---------------------------------------------------------------------------
DR DOSAC-COBS 2D-PAGE; P01023; P01023.
DR DOSAC-COBS-2DPAGE; P01023; A2MG_HUMAN.
DR Siena-2DPAGE; P01023; A2MG_HUMAN.
DR UniProtKB/Swiss-Prot; P01023; A2MG_HUMAN.
//
The following 2-D maps are available for this protein:
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HepG2 Secreted Proteins
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Plasma
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SWISS-2DPAGE (search AC)
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