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Sample Preparation and Post-separation Analysis
| Searching in 'SWISS-2DPAGE' for entry matching: APOE_HUMAN |
SWISS-2DPAGE: APOE_HUMAN
APOE_HUMAN:
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ID APOE_HUMAN; STANDARD; 2DG.
AC P02649;
DT 01-FEB-1995, integrated into SWISS-2DPAGE (release 1).
DT 01-DEC-2000, 2D annotation version 1.
DT 19-MAY-2011, general annotation version 12.
DE RecName: Full=Apolipoprotein E; Short=Apo-E; Flags: Precursor;.
GN Name=APOE;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Hominidae; Homo.
OX NCBI_TaxID=9606;
MT CSF_HUMAN, PLASMA_HUMAN.
IM CSF_HUMAN, PLASMA_HUMAN.
RN [1]
RP MAPPING ON GEL.
RX MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan]
RA Anderson N.L., Anderson N.G.;
RT ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'';
RL Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977).
RN [2]
RP MAPPING ON GEL.
RX MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
RA Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch
RA A., Hochstrasser D.F.;
RT ''''''Inside SWISS-2DPAGE database'';'';'';
RL Electrophoresis 16(1):1131-1151(1995).
CC -!- SUBUNIT: MONOMER
2D -!- MASTER: CSF_HUMAN;
2D -!- PI/MW: SPOT 2D-000C5W=5.07/34489;
2D -!- PI/MW: SPOT 2D-000C6F=5.23/33314;
2D -!- PI/MW: SPOT 2D-000C6Q=5.34/32904;
2D -!- PI/MW: SPOT 2D-000C79=5.47/31940;
2D -!- AMINO ACID COMPOSITION: SPOT 2D-000C6F: A=12.03, B=4.12, F=1.03,
2D G=5.84, H=0.69, I=0.69, K=4.12, L=12.71, M=2.41, P=2.75, R=11.68, S=4.81,
2D T=3.78, V=7.56, Y=1.37, Z=24.40;
2D -!- MAPPING: MATCHING WITH THE PLASMA MASTER GEL [2].
2D -!- MASTER: PLASMA_HUMAN;
2D -!- PI/MW: SPOT 2D-000573=5.24/35320;
2D -!- PI/MW: SPOT 2D-000578=5.35/34966;
2D -!- PI/MW: SPOT 2D-00057M=5.49/34200;
2D -!- NORMAL LEVEL: 30-50 MG/L.
2D -!- PATHOLOGICAL LEVEL: APOE ABNORMALITIES IN TYPE III AND IV HYPERLIPAEMIA.
2D -!- POSITIONAL VARIANTS: APOE 2-2, 2-3, 2-4, 3-3, 3-4 AND 4-4.
2D -!- MAPPING: IMMUNOBLOTTING [1].
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DR DOSAC-COBS 2D-PAGE; P02649; P02649.
DR DOSAC-COBS-2DPAGE; P02649; APOE_HUMAN.
DR UniProtKB/Swiss-Prot; P02649; APOE_HUMAN.
//
The following 2-D maps are available for this protein:
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Cerebrospinal Fluid
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Plasma
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SWISS-2DPAGE (search AC)
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