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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: NKRF_HUMAN



General information about the entry
View entry in simple text format
Entry nameNKRF_HUMAN
Primary accession numberO15226
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=NF-kappa-B-repressing factor; Short=NFkB-repressing factor; AltName: Full=Protein ITBA4; AltName: Full=Transcription factor NRF;.
Gene nameName=NKRF
Synonyms=ITBA4, NRF
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=96301  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtO15226; NKRF_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameNKRF_HUMAN
Primary accession numberO15226
Secondary accession number(s) Q4VC41 Q9UJ91
Sequence was last modified on August 15, 2003 (version 2)
Annotations were last modified on September 21, 2011 (version 114)
Name and origin of the protein
DescriptionRecName: Full=NF-kappa-B-repressing factor; Short=NFkB-repressing factor; AltName: Full=Protein ITBA4; AltName: Full=Transcription factor NRF;
Gene nameName=NKRF
Synonyms=ITBA4, NRF
Encoded onName=NKRF; Synonyms=ITBA4, NRF
KeywordsComplete proteome; DNA-binding; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAJ011812; CAB56459.1; ALT_FRAME; mRNA
EMBLAY208891; AAP43025.1; -; mRNA
EMBLBC040379; AAH40379.1; -; mRNA
EMBLBC047878; AAH47878.1; -; mRNA
EMBLY07707; CAA68976.1; -; mRNA
IPIIPI00005675; -; .
RefSeqNP_001166958.1; NM_001173487.1; .
RefSeqNP_001166959.1; NM_001173488.1; .
RefSeqNP_060014.2; NM_017544.3; .
UniGeneHs.437084; -; .
ProteinModelPortalO15226; -; .
SMRO15226; 339-415; 446-518; 604-663
IntActO15226; 3; .
STRINGO15226; -; .
PhosphoSiteO15226; -; .
SWISS-2DPAGEO15226; -; .
PeptideAtlasO15226; -; .
PRIDEO15226; -; .
EnsemblENST00000304449; ENSP00000304803; ENSG00000186416; .
EnsemblENST00000371527; ENSP00000360582; ENSG00000186416; .
GeneID55922; -; .
KEGGhsa:55922; -; .
UCSCuc004erq.1; human; .
CTD55922; -; .
GeneCardsGC0XM108215; -; .
H-InvDBHIX0203322; -; .
HPAHPA001476; -; .
MIM300440; gene; .
neXtProtNX_O15226; -; .
HOGENOMHBG714785; -; .
HOVERGENHBG052630; -; .
InParanoidO15226; -; .
OrthoDBEOG4M65H5; -; .
PhylomeDBO15226; -; .
NextBio61327; -; .
ArrayExpressO15226; -; .
BgeeO15226; -; .
CleanExHS_NKRF; -; .
GenevestigatorO15226; -; .
GermOnlineENSG00000186416; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IDA:HPA; .
GOGO:0005730; C:nucleolus; IDA:HPA; .
GOGO:0003677; F:DNA binding; IEA:UniProtKB-KW; .
GOGO:0003725; F:double-stranded RNA binding; IEA:InterPro; .
GOGO:0045892; P:negative regulation of transcription; DNA-dependent; IDA:UniProtKB
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
InterProIPR001159; Ds-RNA-bd; .
InterProIPR014720; dsRNA-bd-like; .
InterProIPR000467; G_patch; .
InterProIPR001374; R3H_ss-bd; .
Gene3DG3DSA:; dsRNA-bd-like; 2; .
PfamPF01585; G-patch; 1; .
PfamPF01424; R3H; 1; .
SMARTSM00358; DSRM; 2; .
SMARTSM00443; G_patch; 1; .
SMARTSM00393; R3H; 1; .
PROSITEPS51061; R3H; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server