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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: O00541



General information about the entry
View entry in simple text format
Entry namePESC_HUMAN
Primary accession numberO00541
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Pescadillo homolog;.
Gene nameName=PES1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=68364  [identification data]

MAPPING (identification):
Peptide mass fingerprinting and tandem mass SPECTROMETRY [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtO00541; PESC_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePESC_HUMAN
Primary accession numberO00541
Secondary accession number(s) Q6IC29
Sequence was last modified on July 1, 1997 (version 1)
Annotations were last modified on October 19, 2011 (version 101)
Name and origin of the protein
DescriptionRecName: Full=Pescadillo homolog;
Gene nameName=PES1
Encoded onName=PES1
Keywords3D-structure; Acetylation; Alternative splicing; Chromosome; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ribosome biogenesis; rRNA processing; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLU78310; AAB61140.1; -; mRNA
EMBLCR456539; CAG30425.1; -; mRNA
EMBLBC032489; AAH32489.1; -; mRNA
IPIIPI00003768; -; .
IPIIPI00554461; -; .
RefSeqNP_001230154.1; NM_001243225.1; .
RefSeqNP_055118.1; NM_014303.3; .
UniGeneHs.517543; -; .
PDB2EP8; NMR; -; A=322-414
PDBsum2EP8; -; .
ProteinModelPortalO00541; -; .
SMRO00541; 322-414; .
IntActO00541; 3; .
STRINGO00541; -; .
PhosphoSiteO00541; -; .
SWISS-2DPAGEO00541; -; .
PRIDEO00541; -; .
EnsemblENST00000354694; ENSP00000346725; ENSG00000100029; .
GeneID23481; -; .
KEGGhsa:23481; -; .
UCSCuc003aij.1; human; .
UCSCuc003aik.1; human; .
CTD23481; -; .
GeneCardsGC22M013934; -; .
H-InvDBHIX0203171; -; .
HGNCHGNC:8848; PES1; .
MIM605819; gene; .
neXtProtNX_O00541; -; .
eggNOGprNOG15946; -; .
GeneTreeENSGT00390000002626; -; .
HOGENOMHBG410102; -; .
HOVERGENHBG023409; -; .
InParanoidO00541; -; .
OrthoDBEOG48KRB1; -; .
PhylomeDBO00541; -; .
NextBio45839; -; .
ArrayExpressO00541; -; .
BgeeO00541; -; .
CleanExHS_PES1; -; .
GenevestigatorO00541; -; .
GermOnlineENSG00000100029; Homo sapiens; .
GOGO:0005694; C:chromosome; IEA:UniProtKB-SubCell; .
GOGO:0005654; C:nucleoplasm; IDA:UniProtKB; .
GOGO:0070545; C:PeBoW complex; IDA:UniProtKB; .
GOGO:0030687; C:preribosome; large subunit precursor; IDA:UniProtKB
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0008283; P:cell proliferation; IMP:UniProtKB; .
GOGO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA; 5.8S rRNA; LSU-rRNA)
GOGO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA; 5.8S rRNA; LSU-rRNA)
GOGO:0051726; P:regulation of cell cycle; IMP:UniProtKB; .
InterProIPR001357; BRCT; .
InterProIPR010613; Pescadillo; .
PfamPF00533; BRCT; 1; .
PfamPF06732; Pescadillo_N; 1; .
SMARTSM00292; BRCT; 1; .
SUPFAMSSF52113; BRCT; 1; .
PROSITEPS50172; BRCT; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server