resource logo


Attention: World-2DPAGE is no longer maintained.

Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected

Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: O43143



General information about the entry
View entry in simple text format
Entry nameDHX15_HUMAN
Primary accession numberO43143
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; EC=; AltName: Full=ATP-dependent RNA helicase #46; AltName: Full=DEAH box protein 15;.
Gene nameName=DHX15
Synonyms=DBP1, DDX15
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=87069  [identification data]
Mw=85677  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtO43143; DHX15_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameDHX15_HUMAN
Primary accession numberO43143
Secondary accession number(s) Q9NQT7
Sequence was last modified on February 21, 2001 (version 2)
Annotations were last modified on October 19, 2011 (version 116)
Name and origin of the protein
DescriptionRecName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; EC=; AltName: Full=ATP-dependent RNA helicase #46; AltName: Full=DEAH box protein 15;
Gene nameName=DHX15
Synonyms=DBP1, DDX15
Encoded onName=DHX15; Synonyms=DBP1, DDX15
KeywordsAcetylation; ATP-binding; Complete proteome; Helicase; Hydrolase; mRNA processing; mRNA splicing; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAB001636; BAA23987.1; -; mRNA
EMBLAF279891; AAF90182.1; -; mRNA
EMBLBC035974; AAH35974.1; -; mRNA
IPIIPI00396435; -; .
PIRJC5785; JC5785; .
RefSeqNP_001349.2; NM_001358.2; .
UniGeneHs.696074; -; .
ProteinModelPortalO43143; -; .
SMRO43143; 115-787; .
DIPDIP-38211N; -; .
IntActO43143; 14; .
MINTMINT-5003827; -; .
STRINGO43143; -; .
PhosphoSiteO43143; -; .
SWISS-2DPAGEO43143; -; .
PRIDEO43143; -; .
EnsemblENST00000336812; ENSP00000336741; ENSG00000109606; .
GeneID1665; -; .
KEGGhsa:1665; -; .
UCSCuc003gqx.1; human; .
CTD1665; -; .
GeneCardsGC04M023871; -; .
HGNCHGNC:2738; DHX15; .
MIM603403; gene; .
neXtProtNX_O43143; -; .
PharmGKBPA27204; -; .
eggNOGprNOG11716; -; .
GeneTreeENSGT00550000074627; -; .
HOGENOMHBG757997; -; .
HOVERGENHBG039428; -; .
InParanoidO43143; -; .
OrthoDBEOG4K6G3N; -; .
PhylomeDBO43143; -; .
NextBio6852; -; .
ArrayExpressO43143; -; .
BgeeO43143; -; .
CleanExHS_DHX15; -; .
GenevestigatorO43143; -; .
GermOnlineENSG00000109606; Homo sapiens; .
GOGO:0005689; C:U12-type spliceosomal complex; IDA:HGNC; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0008026; F:ATP-dependent helicase activity; IEA:InterPro; .
GOGO:0003676; F:nucleic acid binding; IEA:InterPro; .
GOGO:0003724; F:RNA helicase activity; TAS:ProtInc; .
GOGO:0006397; P:mRNA processing; TAS:ProtInc; .
GOGO:0008380; P:RNA splicing; IC:HGNC; .
InterProIPR003593; ATPase_AAA+_core; .
InterProIPR014001; DEAD-like_helicase; .
InterProIPR011545; DNA/RNA_helicase_DEAD/DEAH_N; .
InterProIPR002464; DNA/RNA_helicase_DEAH_CS; .
InterProIPR011709; DUF1605; .
InterProIPR007502; Helicase-assoc_dom; .
InterProIPR001650; Helicase_C; .
PfamPF00270; DEAD; 1; .
PfamPF04408; HA2; 1; .
PfamPF00271; Helicase_C; 1; .
PfamPF07717; OB_NTP_bind; 1; .
SMARTSM00382; AAA; 1; .
SMARTSM00487; DEXDc; 1; .
SMARTSM00847; HA2; 1; .
SMARTSM00490; HELICc; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server