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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P18077



General information about the entry
View entry in simple text format
Entry nameRL35A_HUMAN
Primary accession numberP18077
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 4)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L35a; AltName: Full=Cell growth-inhibiting gene 33 protein;.
Gene nameName=RPL35A
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=16579  [identification data]
Mw=16327  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP18077; RL35A_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRL35A_HUMAN
Primary accession numberP18077
Secondary accession number(s) Q08ES9 Q9BVN7
Sequence was last modified on July 26, 2002 (version 2)
Annotations were last modified on October 19, 2011 (version 104)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L35a; AltName: Full=Cell growth-inhibiting gene 33 protein;
Gene nameName=RPL35A
Encoded onName=RPL35A; ORFNames=GIG33
KeywordsAcetylation; Complete proteome; Diamond-Blackfan anemia; Disease mutation; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; tRNA-binding.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX52966; CAA37138.1; -; mRNA
EMBLAY871273; AAX11429.1; -; mRNA
EMBLCH471252; EAW92249.1; -; Genomic_DNA
EMBLBC001037; AAH01037.1; -; mRNA
EMBLBC010949; AAH10949.1; -; mRNA
EMBLBC017093; AAH17093.1; -; mRNA
EMBLBC061890; AAH61890.1; -; mRNA
EMBLX94619; CAA64325.1; -; Genomic_DNA
IPIIPI00029731; -; .
PIRS12710; R5HU35; .
RefSeqNP_000987.2; NM_000996.2; .
UniGeneHs.529631; -; .
ProteinModelPortalP18077; -; .
SMRP18077; 2-103; .
IntActP18077; 4; .
MINTMINT-1163509; -; .
STRINGP18077; -; .
PhosphoSiteP18077; -; .
SWISS-2DPAGEP18077; -; .
PRIDEP18077; -; .
EnsemblENST00000448864; ENSP00000393393; ENSG00000182899; .
EnsemblENST00000464167; ENSP00000419117; ENSG00000182899; .
GeneID6165; -; .
KEGGhsa:6165; -; .
UCSCuc003fyr.1; human; .
CTD6165; -; .
GeneCardsGC03P194979; -; .
H-InvDBHIX0005661; -; .
H-InvDBHIX0017737; -; .
HGNCHGNC:10345; RPL35A; .
MIM180468; gene; .
MIM612528; phenotype; .
neXtProtNX_P18077; -; .
Orphanet124; Blackfan-Diamond disease; .
PharmGKBPA34728; -; .
eggNOGprNOG20232; -; .
GeneTreeENSGT00390000016972; -; .
HOGENOMHBG539420; -; .
HOVERGENHBG054581; -; .
InParanoidP18077; -; .
OrthoDBEOG4FR0T3; -; .
PhylomeDBP18077; -; .
ReactomeREACT_13698; Regulation of beta-cell development; .
ReactomeREACT_15380; Diabetes pathways; .
ReactomeREACT_17015; Metabolism of proteins; .
ReactomeREACT_1762; 3' -UTR-mediated translational regulation; .
ReactomeREACT_21257; Metabolism of RNA; .
ReactomeREACT_6167; Influenza Infection; .
ReactomeREACT_71; Gene Expression; .
NextBio23949; -; .
ArrayExpressP18077; -; .
BgeeP18077; -; .
CleanExHS_RPL35A; -; .
GenevestigatorP18077; -; .
GermOnlineENSG00000182899; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005840; C:ribosome; IEA:UniProtKB-KW; .
GOGO:0003735; F:structural constituent of ribosome; IEA:InterPro; .
GOGO:0000049; F:tRNA binding; IEA:UniProtKB-KW; .
GOGO:0031018; P:endocrine pancreas development; TAS:Reactome; .
GOGO:0016071; P:mRNA metabolic process; TAS:Reactome; .
GOGO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB; .
GOGO:0006364; P:rRNA processing; IMP:UniProtKB; .
GOGO:0006414; P:translational elongation; TAS:Reactome; .
GOGO:0006415; P:translational termination; TAS:Reactome; .
GOGO:0019083; P:viral transcription; TAS:Reactome; .
InterProIPR001780; Ribosomal_L35A; .
InterProIPR018266; Ribosomal_L35Ae_CS; .
InterProIPR009000; Transl_elong_init/rib_B-barrel; .
PANTHERPTHR10902; Ribosomal_L35AE; 1; .
PfamPF01247; Ribosomal_L35Ae; 1; .
ProDomPD012670; Ribosomal_L35Ae; 1; .
SUPFAMSSF50447; Translat_factor; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server