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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P25311




SWISS-2DPAGE:  P25311


P25311


General information about the entry
View entry in simple text format
Entry nameZA2G_HUMAN
Primary accession numberP25311
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 15)
Name and origin of the protein
DescriptionRecName: Full=Zinc-alpha-2-glycoprotein; Short=Zn-alpha-2-GP; Short=Zn-alpha-2-glycoprotein; Flags: Precursor;.
Gene nameName=AZGP1
Synonyms=ZAG, ZNGP1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=78094420; PubMed=271964; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Anderson N.G.
''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';''
Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
Comments
  • SUBUNIT: SINGLE CHAIN
2D PAGE maps for identified proteins
How to interpret a protein

CSF_HUMAN {Cerebrospinal Fluid}
Homo sapiens (Human)
Tissue: Cerebrospinal fluid
CSF_HUMAN
  map experimental info
  protein estimated location
 
CSF_HUMAN

MAP LOCATIONS:
pI=4.75; Mw=43206
pI=4.83; Mw=41665
pI=4.92; Mw=41039

MAPPING (identification):
MATCHING WITH THE PLASMA MASTER GEL [2].



PLASMA_HUMAN {Plasma}
Homo sapiens (Human)
Tissue: Plasma
PLASMA_HUMAN
  map experimental info
  protein estimated location
 
PLASMA_HUMAN

MAP LOCATIONS:
pI=4.80; Mw=42114
pI=4.85; Mw=41831
pI=4.91; Mw=40997
pI=4.97; Mw=40261

NORMAL LEVEL:
20-150 MG/L.

MAPPING (identification):
IMMUNOBLOTTING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEIPI00166729; IPI00166729.
Siena-2DPAGEP25311; ZA2G_HUMAN.
UniProtKB/Swiss-ProtP25311; ZA2G_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameZA2G_HUMAN
Primary accession numberP25311
Secondary accession number(s) D6W5T8 O60386 Q5XKQ4 Q8N4N0
Sequence was last modified on March 23, 2010 (version 2)
Annotations were last modified on September 21, 2011 (version 127)
Name and origin of the protein
DescriptionRecName: Full=Zinc-alpha-2-glycoprotein; Short=Zn-alpha-2-GP; Short=Zn-alpha-2-glycoprotein; Flags: Precursor;
Gene nameName=AZGP1
Synonyms=ZAG, ZNGP1
Encoded onName=AZGP1; Synonyms=ZAG, ZNGP1
Keywords3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX59766; CAA42438.1; ALT_INIT; mRNA
EMBLD14034; BAA03123.1; ALT_INIT; Genomic_DNA
EMBLX69953; CAA49574.1; -; Genomic_DNA
EMBLAC004522; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH236956; EAL23862.1; -; Genomic_DNA
EMBLCH471091; EAW76621.1; -; Genomic_DNA
EMBLCH471091; EAW76622.1; -; Genomic_DNA
EMBLBC005306; AAH05306.1; -; mRNA
EMBLBC033830; AAH33830.1; -; mRNA
EMBLD90427; BAA14417.1; ALT_INIT; mRNA
EMBLM76707; AAA61311.1; ALT_INIT; mRNA
IPIIPI00166729; -; .
PIRA54175; A54175; .
RefSeqNP_001176.1; NM_001185.3; .
UniGeneHs.546239; -; .
PDB1T7V; X-ray; 1.95 A; A=21-298
PDB1T7W; X-ray; 2.70 A; A=21-298
PDB1T7X; X-ray; 3.10 A; A=21-298
PDB1T7Y; X-ray; 2.80 A; A=21-298
PDB1T7Z; X-ray; 3.00 A; A=21-298
PDB1T80; X-ray; 2.10 A; A=21-298
PDB1ZAG; X-ray; 2.80 A; A/B/C/D=25-298
PDB3ES6; X-ray; 3.23 A; A=22-298
PDBsum1T7V; -; .
PDBsum1T7W; -; .
PDBsum1T7X; -; .
PDBsum1T7Y; -; .
PDBsum1T7Z; -; .
PDBsum1T80; -; .
PDBsum1ZAG; -; .
PDBsum3ES6; -; .
ProteinModelPortalP25311; -; .
SMRP25311; 25-298; .
IntActP25311; 3; .
STRINGP25311; -; .
PhosphoSiteP25311; -; .
SWISS-2DPAGEP25311; -; .
REPRODUCTION-2DPAGEIPI00166729; -; .
PRIDEP25311; -; .
EnsemblENST00000292401; ENSP00000292401; ENSG00000160862; .
GeneID563; -; .
KEGGhsa:563; -; .
UCSCuc003ush.1; human; .
CTD563; -; .
GeneCardsGC07M094200; -; .
HGNCHGNC:910; AZGP1; .
HPAHPA012582; -; .
MIM194460; gene; .
neXtProtNX_P25311; -; .
PharmGKBPA25203; -; .
GeneTreeENSGT00550000074273; -; .
HOGENOMHBG506889; -; .
HOVERGENHBG016709; -; .
InParanoidP25311; -; .
OMATYQSWVV; -; .
OrthoDBEOG45QHDM; -; .
PhylomeDBP25311; -; .
NextBio2301; -; .
ArrayExpressP25311; -; .
BgeeP25311; -; .
CleanExHS_AZGP1; -; .
GenevestigatorP25311; -; .
GermOnlineENSG00000160862; Homo sapiens; .
GOGO:0005576; C:extracellular region; NAS:UniProtKB; .
GOGO:0042612; C:MHC class I protein complex; IEA:InterPro; .
GOGO:0005504; F:fatty acid binding; NAS:UniProtKB; .
GOGO:0008320; F:protein transmembrane transporter activity; NAS:UniProtKB; .
GOGO:0004540; F:ribonuclease activity; NAS:UniProtKB; .
GOGO:0019882; P:antigen processing and presentation; IEA:InterPro; .
GOGO:0007155; P:cell adhesion; IDA:UniProtKB; .
GOGO:0006955; P:immune response; IEA:InterPro; .
GOGO:0016042; P:lipid catabolic process; NAS:UniProtKB; .
GOGO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB; .
InterProIPR007110; Ig-like; .
InterProIPR013783; Ig-like_fold; .
InterProIPR003006; Ig/MHC_CS; .
InterProIPR003597; Ig_C1-set; .
InterProIPR011161; MHC_I-like_Ag-recog; .
InterProIPR011162; MHC_I/II-like_Ag-recog; .
InterProIPR001039; MHC_I_a_a1/a2; .
Gene3DG3DSA:2.60.40.10; Ig-like_fold; 1; .
Gene3DG3DSA:3.30.500.10; MHC_I-like_Ag-recog; 1; .
PfamPF07654; C1-set; 1; .
PfamPF00129; MHC_I; 1; .
PRINTSPR01638; MHCCLASSI; .
SMARTSM00407; IGc1; 1; .
SUPFAMSSF54452; MHC_I/II-like_Ag-recog; 1; .
PROSITEPS50835; IG_LIKE; 1; .
PROSITEPS00290; IG_MHC; 1; .



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SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server