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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P02489




SWISS-2DPAGE:  P02489


P02489


General information about the entry
View entry in simple text format
Entry nameCRYAA_HUMAN
Primary accession numberP02489
integrated into SWISS-2DPAGE on September 1, 1997 (release 6)
2D Annotations were last modified onDecember 30, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=Alpha-crystallin A chain; AltName: Full=Heat shock protein beta-4; Short=HspB4; Contains: RecName: Full=Alpha-crystallin A chain, short form;.
Gene nameName=CRYAA
Synonyms=CRYA1, HSPB4
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=97295305; PubMed=9150947; [NCBI, ExPASy, EBI, Israel, Japan]
Sarto C., Marocchi A., Sanchez J.-C., Giannone D., Frutiger S., Golaz O., Wilkins M.R., Doro G., Cappellano F., Hughes G.J., Hochstrasser D.F., Mocarelli P.
''''''Renal cell carcinoma and normal kidney protein expression'';'';''
Electrophoresis 18(1):599-604(1997)
2D PAGE maps for identified proteins
How to interpret a protein

KIDNEY_HUMAN {Kidney}
Homo sapiens (Human)
Tissue: Kidney
KIDNEY_HUMAN
  map experimental info
  protein estimated location
 
KIDNEY_HUMAN

MAP LOCATIONS:
pI=6.85; Mw=17247  [identification data]

MAPPING (identification):
AMINO ACID COMPOSITION ANALYSIS [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
Lens-2DPAGEP02489.
UniProtKB/Swiss-ProtP02489; CRYAA_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCRYAA_HUMAN
Primary accession numberP02489
Sequence was last modified on October 1, 1996 (version 2)
Annotations were last modified on October 19, 2011 (version 129)
Name and origin of the protein
DescriptionRecName: Full=Alpha-crystallin A chain; AltName: Full=Heat shock protein beta-4; Short=HspB4; Contains: RecName: Full=Alpha-crystallin A chain, short form;
Gene nameName=CRYAA
Synonyms=CRYA1, HSPB4
Encoded onName=CRYAA; Synonyms=CRYA1, HSPB4
KeywordsAcetylation; Cataract; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Disulfide bond; Eye lens protein; Glycoprotein; Methylation; Nucleus; Oxidation; Phosphoprotein; Polymorphism; Reference proteome; Sensory transduction; Vision.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU05569; AAA97523.1; -; mRNA
EMBLU66584; AAC50900.1; -; mRNA
EMBLX14789; CAA32891.1; -; mRNA
EMBLBC069528; AAH69528.1; -; mRNA
EMBLM35628; AAA52106.1; -; Genomic_DNA
EMBLM35629; AAA52105.1; -; Genomic_DNA
EMBLAP001748; BAA95535.1; -; Genomic_DNA
IPIIPI00021062; -; .
PIRS03344; CYHUAA; .
RefSeqNP_000385.1; NM_000394.2; .
UniGeneHs.184085; -; .
ProteinModelPortalP02489; -; .
SMRP02489; 59-163; .
DisProtDP00444; -; .
DIPDIP-41265N; -; .
MINTMINT-220977; -; .
STRINGP02489; -; .
GlycoSuiteDBP02489; -; .
PhosphoSiteP02489; -; .
SWISS-2DPAGEP02489; -; .
PeptideAtlasP02489; -; .
PRIDEP02489; -; .
EnsemblENST00000291554; ENSP00000291554; ENSG00000160202; .
GeneID1409; -; .
KEGGhsa:1409; -; .
UCSCuc002zdd.1; human; .
CTD1409; -; .
GeneCardsGC21P030007; -; .
H-InvDBHIX0040917; -; .
HGNCHGNC:2388; CRYAA; .
MIM123580; gene+phenotype; .
MIM604219; phenotype; .
neXtProtNX_P02489; -; .
Orphanet98991; Nuclear cataract; .
Orphanet98995; Zonular cataract; .
PharmGKBPA26906; -; .
eggNOGprNOG20855; -; .
HOGENOMHBG748242; -; .
HOVERGENHBG054766; -; .
InParanoidP02489; -; .
OMAGPKVQSG; -; .
OrthoDBEOG4F1X4B; -; .
PhylomeDBP02489; -; .
NextBio5761; -; .
ArrayExpressP02489; -; .
BgeeP02489; -; .
CleanExHS_CRYAA; -; .
GenevestigatorP02489; -; .
GermOnlineENSG00000160202; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW; .
GOGO:0051082; F:unfolded protein binding; IMP:UniProtKB; .
GOGO:0006916; P:anti-apoptosis; IDA:HGNC; .
GOGO:0032387; P:negative regulation of intracellular transport; IDA:HGNC; .
GOGO:0051260; P:protein homooligomerization; IDA:UniProtKB; .
GOGO:0007601; P:visual perception; IMP:UniProtKB; .
InterProIPR001436; Alpha-crystallin/HSP; .
InterProIPR012274; Alpha-crystallin_A; .
InterProIPR003090; Alpha-crystallin_N; .
InterProIPR002068; Hsp20; .
InterProIPR008978; HSP20-like_chaperone; .
PANTHERPTHR11527:SF36; A-crystallin_A; 1; .
PfamPF00525; Crystallin; 1; .
PfamPF00011; HSP20; 1; .
PIRSFPIRSF036514; Sm_HSP_B1; 1; .
PRINTSPR00299; ACRYSTALLIN; .
SUPFAMSSF49764; HSP20_chap; 1; .
PROSITEPS01031; HSP20; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server