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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P07437 SWISS-2DPAGE:  P07437 P07437 General information about the entry View entry in simple text format Entry name TBB5_HUMAN Primary accession number P07437 integrated into SWISS-2DPAGE on  March 31, 2004 (release 17) 2D Annotations were last modified on March 31, 2004 (version 1) General Annotations were last modified on  May 19, 2011 (version 7) Name and origin of the protein Description RecName: Full=Tubulin beta chain; AltName: Full=Tubulin beta-5 chain;. Gene name Name=TUBB Synonyms=TUBB5 ORFNames=OK/SW-cl.56 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D. ''''''New insights into HIV lymphocyte infection'';'';'' (IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004) Comments SUBUNIT: Dimer of alpha and beta chains 2D PAGE maps for identified proteins How to interpret a protein LYMPHOCYTE_HUMAN {Lymphocytes} Homo sapiens (Human) Tissue: Lymphocyte   map experimental info   protein estimated location   LYMPHOCYTE_HUMAN MAP LOCATIONS: SPOT 2D-001Y2J: pI=4.83; Mw=42552   [identification data] MAPPING (identification): Peptide mass fingerprinting [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references OGP-WWW P07437. REPRODUCTION-2DPAGE P07437; P07437. Siena-2DPAGE P07437; TBB2_HUMAN. UCD-2DPAGE P07437; TBB5_HUMAN. UniProtKB/Swiss-Prot P07437; TBB5_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name TBB5_HUMAN Primary accession number P07437 Secondary accession number(s) P05218 Q8WUC1 Q9CY33 Sequence was last modified on  December 21, 2004 (version 2) Annotations were last modified on  October 19, 2011 (version 141) Name and origin of the protein Description RecName: Full=Tubulin beta chain; AltName: Full=Tubulin beta-5 chain; Gene name Name=TUBB Synonyms=TUBB5 ORFNames=OK/SW-cl.56 Encoded on Name=TUBB; Synonyms=TUBB5; ORFNames=OK/SW-cl.56 Keywords Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Isopeptide bond; Methylation; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J00314; AAB59507.1; -; Genomic_DNA EMBL AF141349; AAD33873.1; -; mRNA EMBL AF070561; AAC28642.1; -; mRNA EMBL AF070593; AAC28650.1; -; mRNA EMBL AF070600; AAC28654.1; -; mRNA EMBL BA000025; BAB63321.1; -; Genomic_DNA EMBL AB088100; BAC54932.1; -; Genomic_DNA EMBL AB062393; BAB93480.1; -; mRNA EMBL BC001938; AAH01938.1; -; mRNA EMBL BC002347; AAH02347.1; -; mRNA EMBL BC005838; AAH05838.1; -; mRNA EMBL BC007605; AAH07605.1; -; mRNA EMBL BC013374; AAH13374.1; -; mRNA EMBL BC019924; AAH19924.1; -; mRNA EMBL BC020946; AAH20946.1; -; mRNA EMBL BC021909; AAH21909.1; -; mRNA EMBL BC070326; AAH70326.1; -; mRNA IPI IPI01019113; -; . PIR A26561; A26561; . RefSeq NP_821133.1; NM_178014.2; . UniGene Hs.636480; -; . UniGene Hs.706187; -; . UniGene Hs.714425; -; . ProteinModelPortal P07437; -; . SMR P07437; 2-427; . IntAct P07437; 26; . MINT MINT-1146393; -; . STRING P07437; -; . PhosphoSite P07437; -; . SWISS-2DPAGE P07437; -; . Cornea-2DPAGE P07437; -; . OGP P07437; -; . REPRODUCTION-2DPAGE P07437; -; . UCD-2DPAGE P07437; -; . PRIDE P07437; -; . Ensembl ENST00000327892; ENSP00000339001; ENSG00000196230; . Ensembl ENST00000383564; ENSP00000373058; ENSG00000183311; . Ensembl ENST00000419792; ENSP00000401317; ENSG00000235067; . Ensembl ENST00000421473; ENSP00000399155; ENSG00000224156; . Ensembl ENST00000422650; ENSP00000400663; ENSG00000229684; . Ensembl ENST00000422674; ENSP00000406811; ENSG00000227739; . Ensembl ENST00000432462; ENSP00000410829; ENSG00000232421; . Ensembl ENST00000436628; ENSP00000410071; ENSG00000232575; . GeneID 203068; -; . KEGG hsa:203068; -; . UCSC uc003nrl.1; human; . CTD 203068; -; . GeneCards GC06P030489; -; . H-InvDB HIX0057935; -; . HGNC HGNC:20778; TUBB; . HPA CAB005417; -; . HPA CAB012406; -; . MIM 191130; gene; . neXtProt NX_P07437; -; . PharmGKB PA358; -; . eggNOG maNOG18649; -; . HOVERGEN HBG000089; -; . InParanoid P07437; -; . OMA RYQGEND; -; . OrthoDB EOG4DFPNJ; -; . PhylomeDB P07437; -; . Reactome REACT_152; Cell Cycle; Mitotic; . DrugBank DB01394; Colchicine; . DrugBank DB00570; Vinblastine; . DrugBank DB00541; Vincristine; . DrugBank DB00361; Vinorelbine; . NextBio 90324; -; . CleanEx HS_TUBB; -; . Genevestigator P07437; -; . GermOnline ENSG00000196230; Homo sapiens; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005874; C:microtubule; TAS:BHF-UCL; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; IEA:InterPro; . GO GO:0042288; F:MHC class I protein binding; IDA:UniProtKB; . GO GO:0051301; P:cell division; TAS:BHF-UCL; . GO GO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL; . GO GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0007018; P:microtubule-based movement; IEA:InterPro; . GO GO:0042267; P:natural killer cell mediated cytotoxicity; NAS:UniProtKB; . GO GO:0051258; P:protein polymerization; IEA:InterPro; . InterPro IPR013838; Beta-tubulin_BS; . InterPro IPR002453; Beta_tubulin; . InterPro IPR008280; Tub_FtsZ_C; . InterPro IPR000217; Tubulin; . InterPro IPR018316; Tubulin/FtsZ_2-layer-sand-dom; . InterPro IPR023123; Tubulin_C; . InterPro IPR017975; Tubulin_CS; . InterPro IPR003008; Tubulin_FtsZ_GTPase; . Gene3D G3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; . Gene3D G3DSA:1.10.287.600; Tubulin_C; 1; . Gene3D G3DSA:3.40.50.1440; Tubulin_FtsZ; 1; . PANTHER PTHR11588; Tubulin; 1; . Pfam PF00091; Tubulin; 1; . Pfam PF03953; Tubulin_C; 1; . PRINTS PR01163; BETATUBULIN; . PRINTS PR01161; TUBULIN; . SMART SM00864; Tubulin; 1; . SMART SM00865; Tubulin_C; 1; . SUPFAM SSF55307; Tub_FtsZ_C; 1; . SUPFAM SSF52490; Tubulin_FtsZ; 1; . PROSITE PS00227; TUBULIN; 1; . PROSITE PS00228; TUBULIN_B_AUTOREG; 1; . SWISS-2DPAGE (search AC)