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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P07437




SWISS-2DPAGE:  P07437


P07437


General information about the entry
View entry in simple text format
Entry nameTBB5_HUMAN
Primary accession numberP07437
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Tubulin beta chain; AltName: Full=Tubulin beta-5 chain;.
Gene nameName=TUBB
Synonyms=TUBB5
ORFNames=OK/SW-cl.56
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
Comments
  • SUBUNIT: Dimer of alpha and beta chains
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=4.83; Mw=42552  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
OGP-WWWP07437.
REPRODUCTION-2DPAGEP07437; P07437.
Siena-2DPAGEP07437; TBB2_HUMAN.
UCD-2DPAGEP07437; TBB5_HUMAN.
UniProtKB/Swiss-ProtP07437; TBB5_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTBB5_HUMAN
Primary accession numberP07437
Secondary accession number(s) P05218 Q8WUC1 Q9CY33
Sequence was last modified on December 21, 2004 (version 2)
Annotations were last modified on October 19, 2011 (version 141)
Name and origin of the protein
DescriptionRecName: Full=Tubulin beta chain; AltName: Full=Tubulin beta-5 chain;
Gene nameName=TUBB
Synonyms=TUBB5
ORFNames=OK/SW-cl.56
Encoded onName=TUBB; Synonyms=TUBB5; ORFNames=OK/SW-cl.56
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Isopeptide bond; Methylation; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLJ00314; AAB59507.1; -; Genomic_DNA
EMBLAF141349; AAD33873.1; -; mRNA
EMBLAF070561; AAC28642.1; -; mRNA
EMBLAF070593; AAC28650.1; -; mRNA
EMBLAF070600; AAC28654.1; -; mRNA
EMBLBA000025; BAB63321.1; -; Genomic_DNA
EMBLAB088100; BAC54932.1; -; Genomic_DNA
EMBLAB062393; BAB93480.1; -; mRNA
EMBLBC001938; AAH01938.1; -; mRNA
EMBLBC002347; AAH02347.1; -; mRNA
EMBLBC005838; AAH05838.1; -; mRNA
EMBLBC007605; AAH07605.1; -; mRNA
EMBLBC013374; AAH13374.1; -; mRNA
EMBLBC019924; AAH19924.1; -; mRNA
EMBLBC020946; AAH20946.1; -; mRNA
EMBLBC021909; AAH21909.1; -; mRNA
EMBLBC070326; AAH70326.1; -; mRNA
IPIIPI01019113; -; .
PIRA26561; A26561; .
RefSeqNP_821133.1; NM_178014.2; .
UniGeneHs.636480; -; .
UniGeneHs.706187; -; .
UniGeneHs.714425; -; .
ProteinModelPortalP07437; -; .
SMRP07437; 2-427; .
IntActP07437; 26; .
MINTMINT-1146393; -; .
STRINGP07437; -; .
PhosphoSiteP07437; -; .
SWISS-2DPAGEP07437; -; .
Cornea-2DPAGEP07437; -; .
OGPP07437; -; .
REPRODUCTION-2DPAGEP07437; -; .
UCD-2DPAGEP07437; -; .
PRIDEP07437; -; .
EnsemblENST00000327892; ENSP00000339001; ENSG00000196230; .
EnsemblENST00000383564; ENSP00000373058; ENSG00000183311; .
EnsemblENST00000419792; ENSP00000401317; ENSG00000235067; .
EnsemblENST00000421473; ENSP00000399155; ENSG00000224156; .
EnsemblENST00000422650; ENSP00000400663; ENSG00000229684; .
EnsemblENST00000422674; ENSP00000406811; ENSG00000227739; .
EnsemblENST00000432462; ENSP00000410829; ENSG00000232421; .
EnsemblENST00000436628; ENSP00000410071; ENSG00000232575; .
GeneID203068; -; .
KEGGhsa:203068; -; .
UCSCuc003nrl.1; human; .
CTD203068; -; .
GeneCardsGC06P030489; -; .
H-InvDBHIX0057935; -; .
HGNCHGNC:20778; TUBB; .
HPACAB005417; -; .
HPACAB012406; -; .
MIM191130; gene; .
neXtProtNX_P07437; -; .
PharmGKBPA358; -; .
eggNOGmaNOG18649; -; .
HOVERGENHBG000089; -; .
InParanoidP07437; -; .
OMARYQGEND; -; .
OrthoDBEOG4DFPNJ; -; .
PhylomeDBP07437; -; .
ReactomeREACT_152; Cell Cycle; Mitotic; .
DrugBankDB01394; Colchicine; .
DrugBankDB00570; Vinblastine; .
DrugBankDB00541; Vincristine; .
DrugBankDB00361; Vinorelbine; .
NextBio90324; -; .
CleanExHS_TUBB; -; .
GenevestigatorP07437; -; .
GermOnlineENSG00000196230; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005874; C:microtubule; TAS:BHF-UCL; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0042288; F:MHC class I protein binding; IDA:UniProtKB; .
GOGO:0051301; P:cell division; TAS:BHF-UCL; .
GOGO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL; .
GOGO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome; .
GOGO:0007018; P:microtubule-based movement; IEA:InterPro; .
GOGO:0042267; P:natural killer cell mediated cytotoxicity; NAS:UniProtKB; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
InterProIPR013838; Beta-tubulin_BS; .
InterProIPR002453; Beta_tubulin; .
InterProIPR008280; Tub_FtsZ_C; .
InterProIPR000217; Tubulin; .
InterProIPR018316; Tubulin/FtsZ_2-layer-sand-dom; .
InterProIPR023123; Tubulin_C; .
InterProIPR017975; Tubulin_CS; .
InterProIPR003008; Tubulin_FtsZ_GTPase; .
Gene3DG3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; .
Gene3DG3DSA:1.10.287.600; Tubulin_C; 1; .
Gene3DG3DSA:3.40.50.1440; Tubulin_FtsZ; 1; .
PANTHERPTHR11588; Tubulin; 1; .
PfamPF00091; Tubulin; 1; .
PfamPF03953; Tubulin_C; 1; .
PRINTSPR01163; BETATUBULIN; .
PRINTSPR01161; TUBULIN; .
SMARTSM00864; Tubulin; 1; .
SMARTSM00865; Tubulin_C; 1; .
SUPFAMSSF55307; Tub_FtsZ_C; 1; .
SUPFAMSSF52490; Tubulin_FtsZ; 1; .
PROSITEPS00227; TUBULIN; 1; .
PROSITEPS00228; TUBULIN_B_AUTOREG; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server