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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P19105




SWISS-2DPAGE:  P19105


P19105


General information about the entry
View entry in simple text format
Entry nameML12A_HUMAN
Primary accession numberP19105
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Myosin regulatory light chain 12A; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;.
Gene nameName=MYL12A
Synonyms=MLCB, MRLC3, RLC
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=20529951; PubMed=11079567; [NCBI, ExPASy, EBI, Israel, Japan]
Jung E., Hoogland C., Chiappe D., Sanchez J.-C., Hochstrasser D.F.
''''''The establishment of a human liver nuclei 2-DE reference map'';'';''
Electrophoresis 21(1):3483-3487(2000)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEI_LIVER_HUMAN {Soluble nuclear proteins and matrix from liver tissue}
Homo sapiens (Human)
Tissue: Liver
NUCLEI_LIVER_HUMAN
  map experimental info
  protein estimated location
 
NUCLEI_LIVER_HUMAN

MAP LOCATIONS:
pI=4.62; Mw=15473  [identification data]
pI=4.66; Mw=14971  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP19105.
UniProtKB/Swiss-ProtP19105; ML12A_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameML12A_HUMAN
Primary accession numberP19105
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 114)
Name and origin of the protein
DescriptionRecName: Full=Myosin regulatory light chain 12A; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;
Gene nameName=MYL12A
Synonyms=MLCB, MRLC3, RLC
Encoded onName=MYL12A; Synonyms=MLCB, MRLC3, RLC
KeywordsAcetylation; Calcium; Complete proteome; Motor protein; Muscle protein; Myosin; Phosphoprotein; Reference proteome; Repeat.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX54304; CAA38201.1; -; mRNA
EMBLBC016372; AAH16372.1; -; mRNA
EMBLBC031972; AAH31972.1; -; mRNA
EMBLBC032748; AAH32748.1; -; mRNA
IPIIPI00220573; -; .
PIRS11493; MOHULP; .
RefSeqNP_006462.1; NM_006471.2; .
UniGeneHs.190086; -; .
ProteinModelPortalP19105; -; .
SMRP19105; 20-167; .
IntActP19105; 9; .
MINTMINT-1159148; -; .
STRINGP19105; -; .
PhosphoSiteP19105; -; .
SWISS-2DPAGEP19105; -; .
OGPP19105; -; .
PRIDEP19105; -; .
EnsemblENST00000217652; ENSP00000217652; ENSG00000101608; .
GeneID10627; -; .
KEGGhsa:10627; -; .
UCSCuc002klr.1; human; .
CTD10627; -; .
GeneCardsGC18P003238; -; .
H-InvDBHIX0014301; -; .
HGNCHGNC:16701; MYL12A; .
HPACAB004503; -; .
MIM609211; gene; .
neXtProtNX_P19105; -; .
PharmGKBPA164723273; -; .
HOGENOMHBG746798; -; .
InParanoidP19105; -; .
OMANYVAFTR; -; .
OrthoDBEOG4FTW1S; -; .
PhylomeDBP19105; -; .
NextBio40378; -; .
ArrayExpressP19105; -; .
BgeeP19105; -; .
GenevestigatorP19105; -; .
GermOnlineENSG00000101608; Homo sapiens; .
GOGO:0016459; C:myosin complex; IEA:UniProtKB-KW; .
GOGO:0005509; F:calcium ion binding; IEA:InterPro; .
InterProIPR018248; EF-hand; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR002048; EF_hand_Ca-bd; .
Gene3DG3DSA:1.10.238.10; EF-Hand_type; 2; .
PfamPF00036; efhand; 1; .
SMARTSM00054; EFh; 2; .
PROSITEPS00018; EF_HAND_1; 1; .
PROSITEPS50222; EF_HAND_2; 3; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server