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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P45376




SWISS-2DPAGE:  P45376


P45376


General information about the entry
View entry in simple text format
Entry nameALDR_MOUSE
Primary accession numberP45376
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Aldose reductase; Short=AR; EC=1.1.1.21; AltName: Full=Aldehyde reductase;.
Gene nameName=Akr1b1
Synonyms=Akr1b3, Aldor1, Aldr1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ISLETS_MOUSE {Pancreatic islet cells}
Mus musculus (Mouse)
Tissue: Pancreatic islet
ISLETS_MOUSE
  map experimental info
  protein estimated location
 
ISLETS_MOUSE

MAP LOCATIONS:
pI=6.75; Mw=36508  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
COMPLUYEAST-2DPAGEP45376; ALDR_MOUSE.
PMMA-2DPAGEP45376.
REPRODUCTION-2DPAGEIPI00223757; IPI00223757.
REPRODUCTION-2DPAGEP45376; P45376.
UniProtKB/Swiss-ProtP45376; ALDR_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameALDR_MOUSE
Primary accession numberP45376
Secondary accession number(s) O70130 Q99KC9
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on September 21, 2011 (version 106)
Name and origin of the protein
DescriptionRecName: Full=Aldose reductase; Short=AR; EC=1.1.1.21; AltName: Full=Aldehyde reductase;
Gene nameName=Akr1b1
Synonyms=Akr1b3, Aldor1, Aldr1
Encoded onName=Akr1b1; Synonyms=Akr1b3, Aldor1, Aldr1
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; NADP; Oxidoreductase; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD32250; BAA06980.1; -; mRNA
EMBLL39795; AAA62176.1; -; mRNA
EMBLU29152; AAA69958.1; -; mRNA
EMBLU89150; AAC13358.1; -; Genomic_DNA
EMBLU89140; AAC13358.1; JOINED; Genomic_DNA
EMBLU89142; AAC13358.1; JOINED; Genomic_DNA
EMBLU89143; AAC13358.1; JOINED; Genomic_DNA
EMBLU89144; AAC13358.1; JOINED; Genomic_DNA
EMBLU89145; AAC13358.1; JOINED; Genomic_DNA
EMBLU89146; AAC13358.1; JOINED; Genomic_DNA
EMBLU89147; AAC13358.1; JOINED; Genomic_DNA
EMBLU89148; AAC13358.1; JOINED; Genomic_DNA
EMBLU89149; AAC13358.1; JOINED; Genomic_DNA
EMBLU93231; AAD32300.1; -; Genomic_DNA
EMBLU93230; AAD32300.1; JOINED; Genomic_DNA
EMBLAB016665; BAA76413.1; -; Genomic_DNA
EMBLBC004725; AAH04725.1; -; mRNA
EMBLBC021655; AAH21655.1; -; mRNA
IPIIPI00223757; -; .
PIRI49484; I49484; .
RefSeqNP_033788.3; NM_009658.3; .
UniGeneMm.451; -; .
ProteinModelPortalP45376; -; .
SMRP45376; 2-315; .
IntActP45376; 2; .
STRINGP45376; -; .
PhosphoSiteP45376; -; .
SWISS-2DPAGEP45376; -; .
COMPLUYEAST-2DPAGEP45376; -; .
PMMA-2DPAGEP45376; -; .
REPRODUCTION-2DPAGEIPI00223757; -; .
REPRODUCTION-2DPAGEP45376; -; .
PRIDEP45376; -; .
EnsemblENSMUST00000102980; ENSMUSP00000100045; ENSMUSG00000001642; .
GeneID11677; -; .
KEGGmmu:11677; -; .
CTD11677; -; .
MGIMGI:1353494; Akr1b3; .
eggNOGroNOG10097; -; .
HOGENOMHBG605727; -; .
HOVERGENHBG000020; -; .
InParanoidP45376; -; .
OMAFLDTWTA; -; .
OrthoDBEOG4VMFFR; -; .
PhylomeDBP45376; -; .
NextBio279311; -; .
BgeeP45376; -; .
GenevestigatorP45376; -; .
GermOnlineENSMUSG00000071414; Mus musculus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI; .
InterProIPR001395; Aldo/ket_red; .
InterProIPR018170; Aldo/ket_reductase_CS; .
InterProIPR020471; Aldo/keto_reductase_subgr; .
InterProIPR023210; NADP_OxRdtase_dom; .
Gene3DG3DSA:3.20.20.100; Aldo/ket_red; 1; .
PANTHERPTHR11732; Aldo/ket_red; 1; .
PfamPF00248; Aldo_ket_red; 1; .
PIRSFPIRSF000097; AKR; 1; .
PRINTSPR00069; ALDKETRDTASE; .
SUPFAMSSF51430; Aldo/ket_red; 1; .
PROSITEPS00798; ALDOKETO_REDUCTASE_1; 1; .
PROSITEPS00062; ALDOKETO_REDUCTASE_2; 1; .
PROSITEPS00063; ALDOKETO_REDUCTASE_3; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server