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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: Q61171




SWISS-2DPAGE:  Q61171


Q61171


General information about the entry
View entry in simple text format
Entry namePRDX2_MOUSE
Primary accession numberQ61171
integrated into SWISS-2DPAGE on October 1, 2001 (release 14)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-2; EC=1.11.1.15; AltName: Full=Thiol-specific antioxidant protein; Short=TSA; AltName: Full=Thioredoxin peroxidase 1; AltName: Full=Thioredoxin-dependent peroxide reductase 1;.
Gene nameName=Prdx2
Synonyms=Tdpx1, Tpx
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11503206; [NCBI, ExPASy, EBI, Israel, Japan]
Lanne B., Potthast F., Hoglund A., Brockenhuus Von Lowenhielm H., Nystrom A.-C., Nilsson F., Dahllof B.
''''''Thiourea enhances mapping of the proteome from murine white adipose tissue'';'';''
Proteomics 1(1):819-828(2001)
[2]   MAPPING ON GEL
Tonella L., Hoogland C., Sanchez J.-C.
Submitted (OCT-2001) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=5.10; Mw=19551

MAPPING (identification):
GEL MATCHING [2] WITH WAT_MOUSE 2-DE MAP FROM LANNE ET AL. [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEQ61171; Q61171.
UCD-2DPAGEQ61171; PRDX2_MOUSE.
UniProtKB/Swiss-ProtQ61171; PRDX2_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePRDX2_MOUSE
Primary accession numberQ61171
Secondary accession number(s) O88376 Q60796 Q9CWJ4 Q9DB49
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 122)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-2; EC=1.11.1.15; AltName: Full=Thiol-specific antioxidant protein; Short=TSA; AltName: Full=Thioredoxin peroxidase 1; AltName: Full=Thioredoxin-dependent peroxide reductase 1;
Gene nameName=Prdx2
Synonyms=Tdpx1, Tpx
Encoded onName=Prdx2; Synonyms=Tdpx1, Tpx
KeywordsAcetylation; Antioxidant; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Oxidoreductase; Peroxidase; Redox-active center; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU51679; AAB01941.1; -; mRNA
EMBLX82067; CAA57566.1; -; mRNA
EMBLU20611; AAA69475.1; -; mRNA
EMBLAF032722; AAC35744.1; -; Genomic_DNA
EMBLAF032718; AAC35744.1; JOINED; Genomic_DNA
EMBLAF032719; AAC35744.1; JOINED; Genomic_DNA
EMBLAF032720; AAC35744.1; JOINED; Genomic_DNA
EMBLAF032721; AAC35744.1; JOINED; Genomic_DNA
EMBLAK005225; BAB23893.1; -; mRNA
EMBLAK008433; BAB25666.1; -; mRNA
EMBLAK010653; BAB27093.1; -; mRNA
EMBLAK088280; BAC40255.1; -; mRNA
EMBLBC002034; AAH02034.1; -; mRNA
EMBLBC081454; AAH81454.1; -; mRNA
IPIIPI00117910; -; .
RefSeqNP_035693.3; NM_011563.5; .
UniGeneMm.347009; -; .
UniGeneMm.393373; -; .
ProteinModelPortalQ61171; -; .
SMRQ61171; 3-198; .
IntActQ61171; 7; .
STRINGQ61171; -; .
PeroxiBase4474; Mm2CysPrx02; .
PhosphoSiteQ61171; -; .
SWISS-2DPAGEQ61171; -; .
REPRODUCTION-2DPAGEQ61171; -; .
UCD-2DPAGEQ61171; -; .
PRIDEQ61171; -; .
EnsemblENSMUST00000005292; ENSMUSP00000005292; ENSMUSG00000005161; .
EnsemblENSMUST00000109733; ENSMUSP00000105355; ENSMUSG00000005161; .
EnsemblENSMUST00000109734; ENSMUSP00000105356; ENSMUSG00000005161; .
EnsemblENSMUST00000164807; ENSMUSP00000126451; ENSMUSG00000005161; .
GeneID21672; -; .
KEGGmmu:21672; -; .
NMPDRfig|10090.3.peg.18891; -; .
UCSCuc009mom.1; mouse; .
CTD7001; -; .
MGIMGI:109486; Prdx2; .
eggNOGmaNOG17890; -; .
GeneTreeENSGT00390000004653; -; .
HOGENOMHBG493509; -; .
HOVERGENHBG000286; -; .
InParanoidQ61171; -; .
OMAKLNYPLA; -; .
OrthoDBEOG4V6ZHJ; -; .
PhylomeDBQ61171; -; .
NextBio300952; -; .
ArrayExpressQ61171; -; .
BgeeQ61171; -; .
CleanExMM_PRDX2; -; .
GenevestigatorQ61171; -; .
GermOnlineENSMUSG00000005161; Mus musculus; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0005515; F:protein binding; IPI:MGI; .
GOGO:0008430; F:selenium binding; TAS:MGI; .
GOGO:0008379; F:thioredoxin peroxidase activity; TAS:MGI; .
GOGO:0000187; P:activation of MAPK activity; IMP:MGI; .
GOGO:0006916; P:anti-apoptosis; IDA:MGI; .
GOGO:0048872; P:homeostasis of number of cells; IMP:MGI; .
GOGO:0042744; P:hydrogen peroxide catabolic process; IMP:MGI; .
GOGO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IMP:MGI; .
GOGO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:MGI; .
GOGO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:MGI; .
GOGO:0045581; P:negative regulation of T cell differentiation; IMP:MGI; .
GOGO:0030194; P:positive regulation of blood coagulation; IMP:BHF-UCL; .
GOGO:0010310; P:regulation of hydrogen peroxide metabolic process; IMP:MGI; .
GOGO:0019430; P:removal of superoxide radicals; IMP:BHF-UCL; .
GOGO:0002536; P:respiratory burst involved in inflammatory response; IMP:MGI; .
GOGO:0032496; P:response to lipopolysaccharide; IMP:MGI; .
GOGO:0042098; P:T cell proliferation; IMP:MGI; .
GOGO:0048538; P:thymus development; IMP:MGI; .
InterProIPR000866; AhpC/TSA; .
InterProIPR024706; Peroxiredoxin_AhpC-typ; .
InterProIPR019479; Peroxiredoxin_C; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
PfamPF10417; 1-cysPrx_C; 1; .
PfamPF00578; AhpC-TSA; 1; .
PIRSFPIRSF000239; AHPC; 1; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS51352; THIOREDOXIN_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server