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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P08670




SWISS-2DPAGE:  P08670


P08670


General information about the entry
View entry in simple text format
Entry nameVIME_HUMAN
Primary accession numberP08670
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 3)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Vimentin;.
Gene nameName=VIM
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
[2]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=58189  [identification data]
Mw=56716  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].



LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=4.94; Mw=43308  [identification data]
pI=4.99; Mw=43286  [identification data]
pI=5.06; Mw=43286  [identification data]

EXPRESSION:
expressed predominantly in CD8 and CD4 lymphocytes [2].

MAPPING (identification):
MALDI tandem mass spectrometry [2].



NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=5.21; Mw=57216  [identification data]
pI=5.27; Mw=57216  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP08670; P08670.
DOSAC-COBS-2DPAGEP08670; VIME_HUMAN.
HSC-2DPAGEP08670; HUMAN.
Lens-2DPAGEP08670.
OGP-WWWP08670.
PHCI-2DPAGEP08670.
REPRODUCTION-2DPAGEP08670; P08670.
REPRODUCTION-2DPAGEIPI00418471; IPI00418471.
Siena-2DPAGEP08670; VIME_HUMAN.
UCD-2DPAGEP08670; VIME_HUMAN.
UniProtKB/Swiss-ProtP08670; VIME_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameVIME_HUMAN
Primary accession numberP08670
Secondary accession number(s) B0YJC2 D3DRU4 Q15867 Q15868 Q15869 Q548L2 Q6LER9 Q8N850 Q96ML2 Q9NTM3
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on October 19, 2011 (version 160)
Name and origin of the protein
DescriptionRecName: Full=Vimentin;
Gene nameName=VIM
Encoded onName=VIM
Keywords3D-structure; Acetylation; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Intermediate filament; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM14144; AAA61279.1; -; Genomic_DNA
EMBLX56134; CAA39600.1; -; mRNA
EMBLAF328728; AAN09720.1; -; mRNA
EMBLZ19554; CAA79613.2; -; mRNA
EMBLAK056766; BAB71275.1; ALT_FRAME; mRNA
EMBLAK097336; BAC05002.1; -; mRNA
EMBLAK290643; BAF83332.1; -; mRNA
EMBLCR407690; CAG28618.1; -; mRNA
EMBLAK222507; BAD96227.1; -; mRNA
EMBLAK222602; BAD96322.1; -; mRNA
EMBLEF445046; ACA06101.1; -; Genomic_DNA
EMBLEF445046; ACA06102.1; -; Genomic_DNA
EMBLAL133415; CAB87963.1; -; Genomic_DNA
EMBLCH471072; EAW86215.1; -; Genomic_DNA
EMBLCH471072; EAW86216.1; -; Genomic_DNA
EMBLBC000163; AAH00163.2; -; mRNA
EMBLBC030573; AAH30573.1; -; mRNA
EMBLBC066956; AAH66956.1; -; mRNA
EMBLX16478; CAA34499.1; -; mRNA
EMBLM18895; AAA61281.2; -; Genomic_DNA
EMBLM18888; AAA61281.2; JOINED; Genomic_DNA
EMBLM18889; AAA61281.2; JOINED; Genomic_DNA
EMBLM18890; AAA61281.2; JOINED; Genomic_DNA
EMBLM18891; AAA61281.2; JOINED; Genomic_DNA
EMBLM18892; AAA61281.2; JOINED; Genomic_DNA
EMBLM18893; AAA61281.2; JOINED; Genomic_DNA
EMBLM18894; AAA61281.2; JOINED; Genomic_DNA
EMBLM25246; AAA61282.1; -; mRNA
IPIIPI00418471; -; .
PIRS13115; A25074; .
RefSeqNP_003371.2; NM_003380.3; .
UniGeneHs.455493; -; .
PDB1GK4; X-ray; 2.30 A; A/B/C/D/E/F=328-411
PDB1GK6; X-ray; 1.90 A; A/B=385-412
PDB1GK7; X-ray; 1.40 A; A=102-138
PDB3G1E; X-ray; 1.83 A; A/B=102-138
PDB3KLT; X-ray; 2.70 A; A/B/C/D=263-334
PDB3OL1; X-ray; 2.81 A; A/B/C/D=144-251
PDBsum1GK4; -; .
PDBsum1GK6; -; .
PDBsum1GK7; -; .
PDBsum3G1E; -; .
PDBsum3KLT; -; .
PDBsum3OL1; -; .
ProteinModelPortalP08670; -; .
SMRP08670; 101-138; 144-248; 263-406
IntActP08670; 91; .
MINTMINT-118802; -; .
STRINGP08670; -; .
PhosphoSiteP08670; -; .
SWISS-2DPAGEP08670; -; .
Aarhus/Ghent-2DPAGE8417; IEF; .
Cornea-2DPAGEP08670; -; .
DOSAC-COBS-2DPAGEP08670; -; .
OGPP08670; -; .
PHCI-2DPAGEP08670; -; .
REPRODUCTION-2DPAGEIPI00418471; -; .
REPRODUCTION-2DPAGEP08670; -; .
UCD-2DPAGEP08670; -; .
PeptideAtlasP08670; -; .
PRIDEP08670; -; .
EnsemblENST00000224237; ENSP00000224237; ENSG00000026025; .
GeneID7431; -; .
KEGGhsa:7431; -; .
UCSCuc001iou.1; human; .
CTD7431; -; .
GeneCardsGC10P017275; -; .
H-InvDBHIX0008682; -; .
H-InvDBHIX0035657; -; .
HGNCHGNC:12692; VIM; .
HPACAB000080; -; .
HPAHPA001762; -; .
MIM193060; gene; .
neXtProtNX_P08670; -; .
Orphanet98984; Pulverulent cataract; .
PharmGKBPA37311; -; .
eggNOGprNOG10698; -; .
HOVERGENHBG013015; -; .
InParanoidP08670; -; .
OMAANRTNEK; -; .
OrthoDBEOG4GHZPD; -; .
PhylomeDBP08670; -; .
Pathway_Interaction_DBaurora_b_pathway; Aurora B signaling; .
Pathway_Interaction_DBcaspase_pathway; Caspase cascade in apoptosis; .
ReactomeREACT_17044; Muscle contraction; .
ReactomeREACT_578; Apoptosis; .
NextBio29104; -; .
PMAP-CutDBP08670; -; .
ArrayExpressP08670; -; .
BgeeP08670; -; .
GenevestigatorP08670; -; .
GermOnlineENSG00000026025; Homo sapiens; .
GOGO:0005829; C:cytosol; IDA:UniProtKB; .
GOGO:0005882; C:intermediate filament; IDA:UniProtKB; .
GOGO:0042802; F:identical protein binding; IPI:IntAct; .
GOGO:0008022; F:protein C-terminus binding; IPI:UniProtKB; .
GOGO:0005200; F:structural constituent of cytoskeleton; IDA:UniProtKB; .
GOGO:0006921; P:cellular component disassembly involved in apoptosis; TAS:Reactome; .
GOGO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; .
GOGO:0030049; P:muscle filament sliding; TAS:Reactome; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR006821; Intermed_filament_DNA-bd; .
InterProIPR018039; Intermediate_filament_CS; .
PANTHERPTHR23239; IF; 1; .
PfamPF00038; Filament; 1; .
PfamPF04732; Filament_head; 1; .
PROSITEPS00226; IF; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server