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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P19388




SWISS-2DPAGE:  P19388


P19388


General information about the entry
View entry in simple text format
Entry nameRPAB1_HUMAN
Primary accession numberP19388
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1; Short=RNA polymerases I, II, and III subunit ABC1; AltName: Full=DNA-directed RNA polymerase II 23 kDa polypeptide; AltName: Full=DNA-directed RNA polymerase II subunit E; AltName: Full=RPB5 homolog; AltName: Full=XAP4;.
Gene nameName=POLR2E
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=6.01; Mw=28212  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEIPI00291093; IPI00291093.
UniProtKB/Swiss-ProtP19388; RPAB1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRPAB1_HUMAN
Primary accession numberP19388
Secondary accession number(s) B2R6L4 D6W5Y1 O43380 Q6PIH5 Q9BT06
Sequence was last modified on October 17, 2006 (version 4)
Annotations were last modified on October 19, 2011 (version 125)
Name and origin of the protein
DescriptionRecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1; Short=RNA polymerases I, II, and III subunit ABC1; AltName: Full=DNA-directed RNA polymerase II 23 kDa polypeptide; AltName: Full=DNA-directed RNA polymerase II subunit E; AltName: Full=RPB5 homolog; AltName: Full=XAP4;
Gene nameName=POLR2E
Encoded onName=POLR2E
KeywordsAcetylation; Complete proteome; Direct protein sequencing; DNA-directed RNA polymerase; Host-virus interaction; Nucleus; Polymorphism; Reference proteome; Transcription.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLJ04965; AAA62401.1; ALT_SEQ; mRNA
EMBLS42643; AAB19339.1; -; mRNA
EMBLD38251; BAA07406.1; -; mRNA
EMBLAK312625; BAG35511.1; -; mRNA
EMBLAC004151; AAC03238.1; -; Genomic_DNA
EMBLCH471139; EAW69548.1; -; Genomic_DNA
EMBLCH471139; EAW69549.1; -; Genomic_DNA
EMBLBC004441; AAH04441.1; -; mRNA
EMBLBC034144; AAH34144.1; -; mRNA
IPIIPI00291093; -; .
PIRS52002; A32618; .
RefSeqNP_002686.2; NM_002695.3; .
UniGeneHs.24301; -; .
ProteinModelPortalP19388; -; .
SMRP19388; 2-210; .
DIPDIP-56N; -; .
IntActP19388; 16; .
MINTMINT-193645; -; .
STRINGP19388; -; .
SWISS-2DPAGEP19388; -; .
REPRODUCTION-2DPAGEIPI00291093; -; .
PeptideAtlasP19388; -; .
PRIDEP19388; -; .
EnsemblENST00000215587; ENSP00000215587; ENSG00000099817; .
GeneID5434; -; .
KEGGhsa:5434; -; .
NMPDRfig|9606.3.peg.15259; -; .
UCSCuc002lre.2; human; .
CTD5434; -; .
GeneCardsGC19M000860; -; .
HGNCHGNC:9192; POLR2E; .
MIM180664; gene; .
neXtProtNX_P19388; -; .
PharmGKBPA33512; -; .
eggNOGprNOG16032; -; .
GeneTreeENSGT00390000013841; -; .
HOGENOMHBG314635; -; .
HOVERGENHBG057019; -; .
InParanoidP19388; -; .
OMAMDDEAET; -; .
OrthoDBEOG479F81; -; .
PhylomeDBP19388; -; .
ReactomeREACT_12472; Regulatory RNA pathways; .
ReactomeREACT_1675; mRNA Processing; .
ReactomeREACT_1788; Transcription; .
ReactomeREACT_1892; Elongation arrest and recovery; .
ReactomeREACT_216; DNA Repair; .
ReactomeREACT_6185; HIV Infection; .
ReactomeREACT_71; Gene Expression; .
ReactomeREACT_769; Pausing and recovery of elongation; .
NextBio21025; -; .
ArrayExpressP19388; -; .
BgeeP19388; -; .
CleanExHS_POLR2E; -; .
GenevestigatorP19388; -; .
GermOnlineENSG00000099817; Homo sapiens; .
GOGO:0005665; C:DNA-directed RNA polymerase II; core complex; IDA:UniProtKB
GOGO:0003677; F:DNA binding; IEA:InterPro; .
GOGO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc; .
GOGO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; .
GOGO:0006370; P:mRNA capping; TAS:Reactome; .
GOGO:0000398; P:nuclear mRNA splicing; via spliceosome; TAS:Reactome
GOGO:0050434; P:positive regulation of viral transcription; TAS:Reactome; .
GOGO:0006468; P:protein phosphorylation; IDA:GOC; .
GOGO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome; .
GOGO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome; .
GOGO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome; .
GOGO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome; .
GOGO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome; .
GOGO:0016032; P:viral reproduction; TAS:Reactome; .
InterProIPR014381; DNA-dir_RNA_pol_RPB5_su; .
InterProIPR005571; RNA_pol_Rpb5_N; .
InterProIPR000783; RNA_pol_subH/Rpb5_C; .
InterProIPR020608; RNA_pol_subH/Rpb5_CS; .
Gene3DG3DSA:3.40.1340.10; RNA_pol_Rpb5_N; 1; .
Gene3DG3DSA:3.90.940.20; RNApol_RPB5; 1; .
PfamPF01191; RNA_pol_Rpb5_C; 1; .
PfamPF03871; RNA_pol_Rpb5_N; 1; .
PIRSFPIRSF000747; RPB5; 1; .
ProDomPD005155; RNA_pol_subH/Rpb5_C; 1; .
SUPFAMSSF53036; RNA_pol_Rpb5_N; 1; .
SUPFAMSSF55287; RNApol_RPB5_like; 1; .
PROSITEPS01110; RNA_POL_H_23KD; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server